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Development of Personalized Nutrition: Applications in Lactose Intolerance Diagnosis and Management.
Porzi, Millie; Burton-Pimentel, Kathryn J; Walther, Barbara; Vergères, Guy.
Afiliação
  • Porzi M; Laboratory of Human Nutrition, Department of Health Sciences and Technology, ETH Zurich, 8092 Zurich, Switzerland.
  • Burton-Pimentel KJ; Agroscope, Federal Department of Economic Affairs, Education and Research EAER, 3003 Bern, Switzerland.
  • Walther B; Agroscope, Federal Department of Economic Affairs, Education and Research EAER, 3003 Bern, Switzerland.
  • Vergères G; Agroscope, Federal Department of Economic Affairs, Education and Research EAER, 3003 Bern, Switzerland.
Nutrients ; 13(5)2021 Apr 29.
Article em En | MEDLINE | ID: mdl-33946892
ABSTRACT
Recent discoveries in the "omics" field and the growing focus on preventive health have opened new avenues for personalized nutrition (PN), which is becoming an important theme in the strategic plans of organizations that are active in healthcare, food, and nutrition research. PN holds great potential for individual health optimization, disease management, public health interventions, and product innovation. However, there are still multiple challenges to overcome before PN can be truly embraced by the public and healthcare stakeholders. The diagnosis and management of lactose intolerance (LI), a common condition with a strong inter-individual component, is explored as an interesting example for the potential role of these technologies and the challenges of PN. From the development of genetic and metabolomic LI diagnostic tests that can be carried out in the home, to advances in the understanding of LI pathology and individualized treatment optimization, PN in LI care has shown substantial progress. However, there are still many research gaps to address, including the understanding of epigenetic regulation of lactase expression and how lactose is metabolized by the gut microbiota, in order to achieve better LI detection and effective therapeutic interventions to reverse the potential health consequences of LI.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ciências da Nutrição / Medicina de Precisão / Intolerância à Lactose Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Revista: Nutrients Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Suíça

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ciências da Nutrição / Medicina de Precisão / Intolerância à Lactose Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Revista: Nutrients Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Suíça