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Dominant mutations in CHK1 cause pronuclear fusion failure and zygote arrest that can be rescued by CHK1 inhibitor.
Zhang, Honghui; Chen, Tailai; Wu, Keliang; Hou, Zhenzhen; Zhao, Shigang; Zhang, Chuanxin; Gao, Yuan; Gao, Ming; Chen, Zi-Jiang; Zhao, Han.
Afiliação
  • Zhang H; Center for Reproductive Medicine, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China.
  • Chen T; National Research Center for Assisted Reproductive Technology and Reproductive Genetics, Shandong University, Jinan, Shandong, China.
  • Wu K; Key laboratory of Reproductive Endocrinology of Ministry of Education, Shandong University, Jinan, Shandong, China.
  • Hou Z; Shandong Provincial Clinical Medicine Research Center for Reproductive Health, Shandong University, Jinan, Shandong, China.
  • Zhao S; Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Shanghai, China.
  • Zhang C; Center for Reproductive Medicine, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
  • Gao Y; Center for Reproductive Medicine, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China.
  • Gao M; National Research Center for Assisted Reproductive Technology and Reproductive Genetics, Shandong University, Jinan, Shandong, China.
  • Chen ZJ; Key laboratory of Reproductive Endocrinology of Ministry of Education, Shandong University, Jinan, Shandong, China.
  • Zhao H; Shandong Provincial Clinical Medicine Research Center for Reproductive Health, Shandong University, Jinan, Shandong, China.
Cell Res ; 31(7): 814-817, 2021 07.
Article em En | MEDLINE | ID: mdl-33953335
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Zigoto / Inibidores de Proteínas Quinases Idioma: En Revista: Cell Res Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Zigoto / Inibidores de Proteínas Quinases Idioma: En Revista: Cell Res Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China País de publicação: Reino Unido