Interplay Between Cognitive and Bowel/Bladder Function in Multiple Sclerosis.
Int Neurourol J
; 25(4): 310-318, 2021 Dec.
Article
em En
| MEDLINE
| ID: mdl-33957715
ABSTRACT
PURPOSE:
The aim of this study was to evaluate the prevalence of bowel/bladder dysfunction in multiple sclerosis (MS) and its associations with cognitive impairment.METHODS:
We prospectively enrolled 150 MS patients. Patients were administered the Symbol Digit Modality Test (SDMT), the Neurogenic Bowel Dysfunction Score (NBDS), and the Actionable Bladder Symptom Screening Tool (ABSST). The associations between bowel/bladder dysfunction and cognitive function were assessed through hierarchical regression models using the SDMT and clinicodemographic features as independent variables and NBDS and ABSST scores as dependent variables.RESULTS:
The prevalence of bowel/bladder deficits was 44.7%, with 26 patients (17.3%) suffering from bowel deficits and 60 patients (40%) from bladder deficits. The total NBDS and ABSST scores were correlated with the SDMT (ß=-0.10, P<0.001 and ß=-0.03, P=0.04, respectively) after correction for demographic features and physical disability.CONCLUSION:
Bowel/bladder disorders are common in MS and are associated with both physical and cognitive disability burdens. As SDMT is embedded into routine clinical assessments, a lower score may warrant investigating bowel/bladder dysfunction due to the strong interplay of these factors.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Tipo de estudo:
Prognostic_studies
/
Risk_factors_studies
Aspecto:
Patient_preference
Idioma:
En
Revista:
Int Neurourol J
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
Itália