Protective Functions of Liver X Receptor &#945; in Established Vulnerable Plaques: Involvement of Regulating Endoplasmic Reticulum-Mediated Macrophage Apoptosis and Efferocytosis.

Che, Xinyu; Xiao, Qingqing; Song, Wei; Zhang, Hengyuan; Sun, Beibei; Geng, Na; Tao, Zhenyu; Shao, Qin; Pu, Jun

Protective Functions of Liver X Receptor α in Established Vulnerable Plaques: Involvement of Regulating Endoplasmic Reticulum-Mediated Macrophage Apoptosis and Efferocytosis.

Che, Xinyu; Xiao, Qingqing; Song, Wei; Zhang, Hengyuan; Sun, Beibei; Geng, Na; Tao, Zhenyu; Shao, Qin; Pu, Jun.

Afiliação

Che X; Department of Cardiology Renji Hospital School of Medicine Shanghai Jiao Tong University Shanghai China.
Xiao Q; Department of Cardiology Renji Hospital School of Medicine Shanghai Jiao Tong University Shanghai China.
Song W; Cardiovascular Department of Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine Shanghai China.
Zhang H; Department of Cardiology Renji Hospital School of Medicine Shanghai Jiao Tong University Shanghai China.
Sun B; Department of Radiology Renji Hospital School of Medicine Shanghai Jiao Tong University Shanghai China.
Geng N; Department of Cardiology Renji Hospital School of Medicine Shanghai Jiao Tong University Shanghai China.
Tao Z; Department of Cardiology Renji Hospital School of Medicine Shanghai Jiao Tong University Shanghai China.
Shao Q; Department of Cardiology Renji Hospital School of Medicine Shanghai Jiao Tong University Shanghai China.
Pu J; Department of Cardiology Renji Hospital School of Medicine Shanghai Jiao Tong University Shanghai China.

J Am Heart Assoc ; 10(10): e018455, 2021 05 18.

Article em En | MEDLINE | ID: mdl-33969692

Assuntos

Apoptose; Artéria Carótida Primitiva/patologia; Estresse do Retículo Endoplasmático/fisiologia; Retículo Endoplasmático/metabolismo; Receptores X do Fígado/metabolismo; Macrófagos/metabolismo; Placa Aterosclerótica/metabolismo; Animais; Doenças das Artérias Carótidas/metabolismo; Doenças das Artérias Carótidas/patologia; Artéria Carótida Primitiva/metabolismo; Células Cultivadas; Modelos Animais de Doenças; Retículo Endoplasmático/patologia; Macrófagos/patologia; Masculino; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Knockout; Placa Aterosclerótica/patologia

Palavras-chave

atherosclerosis; endoplasmic reticulum stress; liver X receptor α; macrophage; vulnerable plaque

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Artéria Carótida Primitiva / Apoptose / Retículo Endoplasmático / Placa Aterosclerótica / Estresse do Retículo Endoplasmático / Receptores X do Fígado / Macrófagos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: J Am Heart Assoc Ano de publicação: 2021 Tipo de documento: Article País de publicação: Reino Unido

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