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Animal medical genetics: a historical perspective on more than 50 years of research into genetic disorders of animals at Massey University.
Jolly, R D; Dittmer, K E; Jones, B R; Worth, A J; Thompson, K G; Johnstone, A C; Palmer, D N; Van de Water, N S; Hemsley, K M; Garrick, D J; Winchester, B G; Walkley, S U.
Afiliação
  • Jolly RD; School of Veterinary Science, Massey University, Palmerston North, New Zealand.
  • Dittmer KE; School of Veterinary Science, Massey University, Palmerston North, New Zealand.
  • Jones BR; School of Veterinary Science, Massey University, Palmerston North, New Zealand.
  • Worth AJ; School of Veterinary Science, Massey University, Palmerston North, New Zealand.
  • Thompson KG; School of Veterinary Science, Massey University, Palmerston North, New Zealand.
  • Johnstone AC; School of Veterinary Science, Massey University, Palmerston North, New Zealand.
  • Palmer DN; Faculty of Agriculture and Life Sciences, Lincoln University, Lincoln, New Zealand.
  • Van de Water NS; Department of Diagnostic Genetics, Auckland City Hospital, Auckland District Health Board, Auckland, New Zealand.
  • Hemsley KM; Childhood Dementia Research Group, South Australian Health and Medical Research Institute, Adelaide, Australia.
  • Garrick DJ; School of Agriculture & Environment, Al Rae Centre for Genetics and Breeding, Massey University, Hamilton, New Zealand.
  • Winchester BG; UCL Great Ormond Street Institute of Child Health, London, UK.
  • Walkley SU; School of Veterinary Science, Massey University, Palmerston North, New Zealand.
N Z Vet J ; 69(5): 255-266, 2021 Sep.
Article em En | MEDLINE | ID: mdl-33969809
Over the last 50 years, there have been major advances in knowledge and technology regarding genetic diseases, and the subsequent ability to control them in a cost-effective manner. This review traces these advances through research into genetic diseases of animals at Massey University (Palmerston North, NZ), and briefly discusses the disorders investigated during that time, with additional detail for disorders of major importance such as bovine α-mannosidosis, ovine ceroid-lipofuscinosis, canine mucopolysaccharidosis IIIA and feline hyperchylomicronaemia. The overall research has made a significant contribution to veterinary medicine, has provided new biological knowledge and advanced our understanding of similar disorders in human patients, including testing various specific therapies prior to human clinical trials.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças dos Ovinos / Doenças do Gato / Doenças dos Bovinos / Doenças do Cão / Lipofuscinoses Ceroides Neuronais Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: N Z Vet J Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Nova Zelândia País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças dos Ovinos / Doenças do Gato / Doenças dos Bovinos / Doenças do Cão / Lipofuscinoses Ceroides Neuronais Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: N Z Vet J Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Nova Zelândia País de publicação: Reino Unido