3,4,5­Trihydroxycinnamic acid exerts anti­inflammatory effects on TNF­&#945;/IFN­Î³­stimulated HaCaT cells.

Park, Ji-Won; Oh, Jae-Hoon; Hwang, Daseul; Kim, Seong-Man; Min, Jae-Hong; Seo, Ji-Yun; Chun, Wanjoo; Lee, Hee Jae; Oh, Sei-Ryang; Lee, Jae-Won; Ahn, Kyung-Seop

3,4,5Trihydroxycinnamic acid exerts antiinflammatory effects on TNFα/IFNÎ³stimulated HaCaT cells.

Park, Ji-Won; Oh, Jae-Hoon; Hwang, Daseul; Kim, Seong-Man; Min, Jae-Hong; Seo, Ji-Yun; Chun, Wanjoo; Lee, Hee Jae; Oh, Sei-Ryang; Lee, Jae-Won; Ahn, Kyung-Seop.

Afiliação

Park JW; Natural Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Cheongju, Chungcheongbukdo 28116, Republic of Korea.
Oh JH; Natural Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Cheongju, Chungcheongbukdo 28116, Republic of Korea.
Hwang D; Natural Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Cheongju, Chungcheongbukdo 28116, Republic of Korea.
Kim SM; Natural Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Cheongju, Chungcheongbukdo 28116, Republic of Korea.
Min JH; Natural Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Cheongju, Chungcheongbukdo 28116, Republic of Korea.
Seo JY; Natural Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Cheongju, Chungcheongbukdo 28116, Republic of Korea.
Chun W; Department of Pharmacology, College of Medicine, Kangwon National University, Chuncheon, Gangwondo 24341, Republic of Korea.
Lee HJ; Department of Pharmacology, College of Medicine, Kangwon National University, Chuncheon, Gangwondo 24341, Republic of Korea.
Oh SR; Natural Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Cheongju, Chungcheongbukdo 28116, Republic of Korea.
Lee JW; Natural Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Cheongju, Chungcheongbukdo 28116, Republic of Korea.
Ahn KS; Natural Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Cheongju, Chungcheongbukdo 28116, Republic of Korea.

Mol Med Rep ; 24(1)2021 07.

Article em En | MEDLINE | ID: mdl-33982762

Assuntos

Anti-Inflamatórios/farmacologia; Cinamatos/farmacologia; Interferon gama/farmacologia; Queratinócitos/efeitos dos fármacos; Fator de Necrose Tumoral alfa/farmacologia; Proteínas ADAM/genética; Proteínas ADAM/metabolismo; Quimiocina CCL17/genética; Quimiocina CCL17/metabolismo; Quimiocina CCL2/genética; Quimiocina CCL2/metabolismo; Quimiocina CCL5/genética; Quimiocina CCL5/metabolismo; Células HaCaT; Heme Oxigenase-1/metabolismo; Humanos; Interleucina-6/genética; Interleucina-6/metabolismo; Interleucina-8/genética; Interleucina-8/metabolismo; Proteínas Quinases Ativadas por Mitógeno/metabolismo; NAD(P)H Desidrogenase (Quinona)/metabolismo; Fator 2 Relacionado a NF-E2/metabolismo; Fosforilação/efeitos dos fármacos; Proteínas Proto-Oncogênicas c-akt/metabolismo; Fator de Transcrição RelA/metabolismo; Proteínas Supressoras de Tumor/genética; Proteínas Supressoras de Tumor/metabolismo

Palavras-chave

3; 4; 5trihydroxycinnamic acid; atopic dermatitis; inflammatory molecules; nuclear factorκB

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Queratinócitos / Interferon gama / Fator de Necrose Tumoral alfa / Cinamatos / Anti-Inflamatórios Limite: Humans Idioma: En Revista: Mol Med Rep Ano de publicação: 2021 Tipo de documento: Article País de publicação: Grécia

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