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Bile acid synthesis, modulation, and dementia: A metabolomic, transcriptomic, and pharmacoepidemiologic study.
Varma, Vijay R; Wang, Youjin; An, Yang; Varma, Sudhir; Bilgel, Murat; Doshi, Jimit; Legido-Quigley, Cristina; Delgado, João C; Oommen, Anup M; Roberts, Jackson A; Wong, Dean F; Davatzikos, Christos; Resnick, Susan M; Troncoso, Juan C; Pletnikova, Olga; O'Brien, Richard; Hak, Eelko; Baak, Brenda N; Pfeiffer, Ruth; Baloni, Priyanka; Mohmoudiandehkordi, Siamak; Nho, Kwangsik; Kaddurah-Daouk, Rima; Bennett, David A; Gadalla, Shahinaz M; Thambisetty, Madhav.
Afiliação
  • Varma VR; Clinical and Translational Neuroscience Section, Laboratory of Behavioral Neuroscience, National Institute on Aging (NIA), National Institutes of Health (NIH), Baltimore, Maryland, United States of America.
  • Wang Y; Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America.
  • An Y; Brain Aging and Behavior Section, Laboratory of Behavioral Neuroscience, National Institute on Aging (NIA), National Institutes of Health (NIH), Baltimore, Maryland, United States of America.
  • Varma S; HiThru Analytics, Laurel, Maryland, United States of America.
  • Bilgel M; Brain Aging and Behavior Section, Laboratory of Behavioral Neuroscience, National Institute on Aging (NIA), National Institutes of Health (NIH), Baltimore, Maryland, United States of America.
  • Doshi J; Section for Biomedical Image Analysis, Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
  • Legido-Quigley C; Kings College London, United Kingdom.
  • Delgado JC; College of Medicine and Health, University of Exeter, Exeter, United Kingdom.
  • Oommen AM; Glycoscience Group, NCBES National Centre for Biomedical Engineering Science, National University of Ireland Galway, Galway, Ireland.
  • Roberts JA; Clinical and Translational Neuroscience Section, Laboratory of Behavioral Neuroscience, National Institute on Aging (NIA), National Institutes of Health (NIH), Baltimore, Maryland, United States of America.
  • Wong DF; Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.
  • Davatzikos C; Section for Biomedical Image Analysis, Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
  • Resnick SM; Brain Aging and Behavior Section, Laboratory of Behavioral Neuroscience, National Institute on Aging (NIA), National Institutes of Health (NIH), Baltimore, Maryland, United States of America.
  • Troncoso JC; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.
  • Pletnikova O; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.
  • O'Brien R; Department of Neurology, Duke University School of Medicine, Durham, North Carolina, United States of America.
  • Hak E; Groningen Research Institute of Pharmacy, University of Groningen, Groningen, the Netherlands.
  • Baak BN; Groningen Research Institute of Pharmacy, University of Groningen, Groningen, the Netherlands.
  • Pfeiffer R; Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America.
  • Baloni P; Institute for Systems Biology, Seattle, Washington, United States of America.
  • Mohmoudiandehkordi S; Department of Psychiatry and Behavioral Sciences, Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America.
  • Nho K; Department of Radiology and Imaging Sciences and the Indiana Alzheimer Disease Center, Indiana University School of Medicine, Indianapolis, Indiana, United States of America.
  • Kaddurah-Daouk R; Department of Psychiatry and Behavioral Sciences, Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America.
  • Bennett DA; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, United States of America.
  • Gadalla SM; Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America.
  • Thambisetty M; Clinical and Translational Neuroscience Section, Laboratory of Behavioral Neuroscience, National Institute on Aging (NIA), National Institutes of Health (NIH), Baltimore, Maryland, United States of America.
PLoS Med ; 18(5): e1003615, 2021 05.
Article em En | MEDLINE | ID: mdl-34043628

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ácidos e Sais Biliares / Demência Tipo de estudo: Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Aged / Aged80 / Female / Humans / Male / Middle aged País/Região como assunto: Europa Idioma: En Revista: PLoS Med Assunto da revista: MEDICINA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ácidos e Sais Biliares / Demência Tipo de estudo: Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Aged / Aged80 / Female / Humans / Male / Middle aged País/Região como assunto: Europa Idioma: En Revista: PLoS Med Assunto da revista: MEDICINA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos