Herb-partitioned moxibustion alleviates colonic inflammation in Crohn's disease rats by inhibiting hyperactivation of the NLRP3 inflammasome via regulation of the P2X7R-Pannexin-1 signaling pathway.

Zhang, Ji; Wang, Xue-Jun; Wu, Li-Jie; Yang, Ling; Yang, Yan-Ting; Zhang, Dan; Hong, Jue; Li, Xi-Ying; Dong, Xiao-Qing; Guo, Xiao-Cong; Han, Rong; Ma, Xiaopeng

Zhang, Ji; Wang, Xue-Jun; Wu, Li-Jie; Yang, Ling; Yang, Yan-Ting; Zhang, Dan; Hong, Jue; Li, Xi-Ying; Dong, Xiao-Qing; Guo, Xiao-Cong; Han, Rong; Ma, Xiaopeng.

Afiliação

Zhang J; Yueyang Clinical Medicine School, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Wang XJ; Yueyang Clinical Medicine School, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Wu LJ; Yueyang Clinical Medicine School, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Yang L; Acupuncture and Moxibustion Department, Zhejiang Provincial Hospital of Traditional Chinese Medicine, Hangzhou, Zhejiang, China.
Yang YT; Key Laboratory of Acupuncture-Moxibustion and Immunology, Shanghai Research Institute of Acupuncture and Meridian, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Zhang D; Key Laboratory of Acupuncture-Moxibustion and Immunology, Shanghai Research Institute of Acupuncture and Meridian, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Hong J; Key Laboratory of Acupuncture-Moxibustion and Immunology, Shanghai Research Institute of Acupuncture and Meridian, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Li XY; Key Laboratory of Acupuncture-Moxibustion and Immunology, Shanghai Research Institute of Acupuncture and Meridian, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Dong XQ; Yueyang Clinical Medicine School, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Guo XC; Yueyang Clinical Medicine School, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Han R; Yueyang Clinical Medicine School, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Ma X; Yueyang Clinical Medicine School, Shanghai University of Traditional Chinese Medicine, Shanghai, China.

PLoS One ; 16(5): e0252334, 2021.

Article em En | MEDLINE | ID: mdl-34043726

Assuntos

Conexinas/metabolismo; Doença de Crohn/terapia; Moxibustão/métodos; Proteína 3 que Contém Domínio de Pirina da Família NLR/metabolismo; Proteínas do Tecido Nervoso/metabolismo; Receptores Purinérgicos P2X7/metabolismo; Animais; Ratos; Ratos Sprague-Dawley

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Crohn / Conexinas / Receptores Purinérgicos P2X7 / Proteína 3 que Contém Domínio de Pirina da Família NLR / Moxibustão / Proteínas do Tecido Nervoso Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China País de publicação: Estados Unidos

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