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A genetic variant in telomerase reverse transcriptase (TERT) modifies cancer risk in Lynch syndrome patients harbouring pathogenic MSH2 variants.
Wiik, Mariann Unhjem; Evans, Tiffany-Jane; Belhadj, Sami; Bolton, Katherine A; Dymerska, Dagmara; Jagmohan-Changur, Shantie; Capellá, Gabriel; Kurzawski, Grzegorz; Wijnen, Juul T; Valle, Laura; Vasen, Hans F A; Lubinski, Jan; Scott, Rodney J; Talseth-Palmer, Bente A.
Afiliação
  • Wiik MU; Research Unit, Ålesund Hospital, Møre and Romsdal Hospital Trust, Ålesund, Norway.
  • Evans TJ; Hunter Medical Research Institute, New Lambton Heights, Australia.
  • Belhadj S; Hereditary Cancer Program, Catalan Institute of Oncology, IDIBELL and CIBERONC, Hospitalet de Llobregat, Barcelona, Spain.
  • Bolton KA; School of Biomedical Science and Pharmacy, Faculty of Health and Medicine, University of Newcastle, Newcastle, NSW, Australia.
  • Dymerska D; Department of Genetics and Pathology, International Hereditary Cancer Center, Pomeranian Medical University, Szczecin, Poland.
  • Jagmohan-Changur S; Department of Human Genetics, Leiden University Medical Center, Leiden, the Netherlands.
  • Capellá G; Hereditary Cancer Program, Catalan Institute of Oncology, IDIBELL and CIBERONC, Hospitalet de Llobregat, Barcelona, Spain.
  • Kurzawski G; Department of Genetics and Pathology, International Hereditary Cancer Center, Pomeranian Medical University, Szczecin, Poland.
  • Wijnen JT; Department of Human Genetics, Leiden University Medical Center, Leiden, the Netherlands.
  • Valle L; Hereditary Cancer Program, Catalan Institute of Oncology, IDIBELL and CIBERONC, Hospitalet de Llobregat, Barcelona, Spain.
  • Vasen HFA; Department of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, the Netherlands.
  • Lubinski J; Department of Genetics and Pathology, International Hereditary Cancer Center, Pomeranian Medical University, Szczecin, Poland.
  • Scott RJ; Hunter Medical Research Institute, New Lambton Heights, Australia.
  • Talseth-Palmer BA; School of Biomedical Science and Pharmacy, Faculty of Health and Medicine, University of Newcastle, Newcastle, NSW, Australia.
Sci Rep ; 11(1): 11401, 2021 05 31.
Article em En | MEDLINE | ID: mdl-34059744
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Neoplasias Colorretais Hereditárias sem Polipose / DNA Polimerase Dirigida por RNA / Telomerase / Predisposição Genética para Doença / Proteína 2 Homóloga a MutS Tipo de estudo: Etiology_studies / Guideline / Risk_factors_studies Limite: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Sci Rep Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Noruega País de publicação: Reino Unido
Texto completo
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PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Neoplasias Colorretais Hereditárias sem Polipose / DNA Polimerase Dirigida por RNA / Telomerase / Predisposição Genética para Doença / Proteína 2 Homóloga a MutS Tipo de estudo: Etiology_studies / Guideline / Risk_factors_studies Limite: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Sci Rep Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Noruega País de publicação: Reino Unido