ConNEcT: A Novel Network Approach for Investigating the Co-occurrence of Binary Psychopathological Symptoms Over Time.
Psychometrika
; 87(1): 107-132, 2022 03.
Article
em En
| MEDLINE
| ID: mdl-34061286
ABSTRACT
Network analysis is an increasingly popular approach to study mental disorders in all their complexity. Multiple methods have been developed to extract networks from cross-sectional data, with these data being either continuous or binary. However, when it comes to time series data, most efforts have focused on continuous data. We therefore propose ConNEcT, a network approach for binary symptom data across time. ConNEcT allows to visualize and study the prevalence of different symptoms as well as their co-occurrence, measured by means of a contingency measure in one single network picture. ConNEcT can be complemented with a significance test that accounts for the serial dependence in the data. To illustrate the usefulness of ConNEcT, we re-analyze data from a study in which patients diagnosed with major depressive disorder weekly reported the absence or presence of eight depression symptoms. We first extract ConNEcTs for all patients that provided data during at least 104 weeks, revealing strong inter-individual differences in which symptom pairs co-occur significantly. Second, to gain insight into these differences, we apply Hierarchical Classes Analysis on the co-occurrence patterns of all patients, showing that they can be grouped into meaningful clusters. Core depression symptoms (i.e., depressed mood and/or diminished interest), cognitive problems and loss of energy seem to co-occur universally, but preoccupation with death, psychomotor problems or eating problems only co-occur with other symptoms for specific patient subgroups.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Transtorno Depressivo Maior
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Transtornos Mentais
Tipo de estudo:
Diagnostic_studies
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Observational_studies
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Prevalence_studies
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Risk_factors_studies
Limite:
Humans
Idioma:
En
Revista:
Psychometrika
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
Bélgica
País de publicação:
EEUU
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ESTADOS UNIDOS
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ESTADOS UNIDOS DA AMERICA
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EUA
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UNITED STATES
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UNITED STATES OF AMERICA
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US
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USA