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New nimesulide derivatives with amide/sulfonamide moieties: Selective COX-2 inhibition and antitumor effects.
Güngör, Tugba; Ozleyen, Adem; Yilmaz, Yakup Berkay; Siyah, Pinar; Ay, Mehmet; Durdagi, Serdar; Tumer, Tugba Boyunegmez.
Afiliação
  • Güngör T; Department of Chemistry, Faculty of Sciences and Arts, Natural Products and Drug Research Laboratory, Çanakkale Onsekiz Mart University, Çanakkale, 17020, Turkey. Electronic address: tgungor@comu.edu.tr.
  • Ozleyen A; Graduate Program of Biomolecular Sciences, School of Graduate Studies, Canakkale Onsekiz Mart University, 17020, Çanakkale, Turkey; School of Chemistry, University of Leicester, LE1 7RH, Leicester, United Kingdom.
  • Yilmaz YB; Graduate Program of Biomolecular Sciences, School of Graduate Studies, Canakkale Onsekiz Mart University, 17020, Çanakkale, Turkey; Department of Molecular Biology and Genetics, Faculty of Arts and Science, Çanakkale Onsekiz Mart University, 17020, Çanakkale, Turkey.
  • Siyah P; Computational Biology and Molecular Simulations Laboratory, Department of Biophysics, School of Medicine, Bahçesehir University, 34353, Istanbul, Turkey.
  • Ay M; Department of Chemistry, Faculty of Sciences and Arts, Natural Products and Drug Research Laboratory, Çanakkale Onsekiz Mart University, Çanakkale, 17020, Turkey.
  • Durdagi S; Computational Biology and Molecular Simulations Laboratory, Department of Biophysics, School of Medicine, Bahçesehir University, 34353, Istanbul, Turkey.
  • Tumer TB; Department of Molecular Biology and Genetics, Faculty of Arts and Science, Çanakkale Onsekiz Mart University, 17020, Çanakkale, Turkey. Electronic address: tumertb@comu.edu.tr.
Eur J Med Chem ; 221: 113566, 2021 Oct 05.
Article em En | MEDLINE | ID: mdl-34077833
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sulfonamidas / Ciclo-Oxigenase 2 / Inibidores de Ciclo-Oxigenase 2 / Amidas / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Eur J Med Chem Ano de publicação: 2021 Tipo de documento: Article País de publicação: França
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sulfonamidas / Ciclo-Oxigenase 2 / Inibidores de Ciclo-Oxigenase 2 / Amidas / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Eur J Med Chem Ano de publicação: 2021 Tipo de documento: Article País de publicação: França