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Fe-S cofactors in the SARS-CoV-2 RNA-dependent RNA polymerase are potential antiviral targets.
Maio, Nunziata; Lafont, Bernard A P; Sil, Debangsu; Li, Yan; Bollinger, J Martin; Krebs, Carsten; Pierson, Theodore C; Linehan, W Marston; Rouault, Tracey A.
Afiliação
  • Maio N; Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.
  • Lafont BAP; SARS-CoV-2 Virology Core, Laboratory of Viral Diseases, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
  • Sil D; Department of Chemistry, The Pennsylvania State University, University Park, PA 16802, USA.
  • Li Y; Proteomics Core Facility, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA.
  • Bollinger JM; Department of Chemistry, The Pennsylvania State University, University Park, PA 16802, USA.
  • Krebs C; Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, PA 16802, USA.
  • Pierson TC; Department of Chemistry, The Pennsylvania State University, University Park, PA 16802, USA.
  • Linehan WM; Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, PA 16802, USA.
  • Rouault TA; Laboratory of Viral Diseases, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
Science ; 373(6551): 236-241, 2021 07 09.
Article em En | MEDLINE | ID: mdl-34083449
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Enxofre / Coenzimas / Óxidos N-Cíclicos / RNA-Polimerase RNA-Dependente de Coronavírus / SARS-CoV-2 / Ferro Limite: Animals Idioma: En Revista: Science Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Enxofre / Coenzimas / Óxidos N-Cíclicos / RNA-Polimerase RNA-Dependente de Coronavírus / SARS-CoV-2 / Ferro Limite: Animals Idioma: En Revista: Science Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos