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Inhibition of EZH2 primes the cardiac gene activation via removal of epigenetic repression during human direct cardiac reprogramming.
Tang, Yawen; Zhao, Lianzhong; Yu, Xufen; Zhang, Jianyi; Qian, Li; Jin, Jian; Lu, Rui; Zhou, Yang.
Afiliação
  • Tang Y; Department of Biomedical Engineering, University of Alabama at Birmingham, Birmingham, AL 35233, USA.
  • Zhao L; Division of Hematology/Oncology, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA; O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
  • Yu X; Mount Sinai Center for Therapeutics Discovery, Departments of Pharmacological Sciences and Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Zhang J; Department of Biomedical Engineering, University of Alabama at Birmingham, Birmingham, AL 35233, USA.
  • Qian L; Department of Pathology and Laboratory Medicine, McAllister Heart Institute, Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC 27599, USA.
  • Jin J; Mount Sinai Center for Therapeutics Discovery, Departments of Pharmacological Sciences and Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Lu R; Division of Hematology/Oncology, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA; O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
  • Zhou Y; Department of Biomedical Engineering, University of Alabama at Birmingham, Birmingham, AL 35233, USA. Electronic address: yangzhou@uab.edu.
Stem Cell Res ; 53: 102365, 2021 05.
Article em En | MEDLINE | ID: mdl-34087994
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Repressão Epigenética / Proteína Potenciadora do Homólogo 2 de Zeste Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Stem Cell Res Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Repressão Epigenética / Proteína Potenciadora do Homólogo 2 de Zeste Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Stem Cell Res Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido