Racemization in cataractous lens from diabetic and aging individuals: analysis of Asp 58 residue in &#945;A-crystallin.

Zhu, Xiang-Jia; Zhang, Ke-Ke; He, Wen-Wen; Qi, Jiao; Lu, Yi

Racemization in cataractous lens from diabetic and aging individuals: analysis of Asp 58 residue in αA-crystallin.

Zhu, Xiang-Jia; Zhang, Ke-Ke; He, Wen-Wen; Qi, Jiao; Lu, Yi.

Afiliação

Zhu XJ; Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai 200031, People's Republic of China.
Zhang KK; NHC Key Laboratory of Myopia, Key Laboratory of Myopia, Chinese Academy of Medical Sciences, Fudan University, Shanghai 200031, People's Republic of China.
He WW; Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai 200031, People's Republic of China.
Qi J; Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai 200031, People's Republic of China.
Lu Y; NHC Key Laboratory of Myopia, Key Laboratory of Myopia, Chinese Academy of Medical Sciences, Fudan University, Shanghai 200031, People's Republic of China.

Aging (Albany NY) ; 13(11): 15255-15268, 2021 06 07.

Article em En | MEDLINE | ID: mdl-34096886

Assuntos

Ácido Aspártico/metabolismo; Catarata/patologia; Cristalinas/química; Cristalino/patologia; Idoso; Envelhecimento/patologia; Núcleo Celular/metabolismo; Feminino; Humanos; Isomerismo; Masculino; Solubilidade

Palavras-chave

aging; aspartyl residue; cataract; crystallin; diabetes; lens; racemization

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Catarata / Ácido Aspártico / Cristalinas / Cristalino Limite: Aged / Female / Humans / Male Idioma: En Revista: Aging (Albany NY) Assunto da revista: GERIATRIA Ano de publicação: 2021 Tipo de documento: Article País de publicação: Estados Unidos

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