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Discovery of PF-06873600, a CDK2/4/6 Inhibitor for the Treatment of Cancer.
Freeman-Cook, Kevin D; Hoffman, Robert L; Behenna, Douglas C; Boras, Britton; Carelli, Jordan; Diehl, Wade; Ferre, Rose Ann; He, You-Ai; Hui, Andrea; Huang, Buwen; Huser, Nanni; Jones, Rhys; Kephart, Susan E; Lapek, John; McTigue, Michele; Miller, Nichol; Murray, Brion W; Nagata, Asako; Nguyen, Lisa; Niessen, Sherry; Ninkovic, Sacha; O'Doherty, Inish; Ornelas, Martha A; Solowiej, James; Sutton, Scott C; Tran, Khanh; Tseng, Elaine; Visswanathan, Ravi; Xu, Meirong; Zehnder, Luke; Zhang, Qin; Zhang, Cathy; Dann, Stephen.
Afiliação
  • Freeman-Cook KD; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States.
  • Hoffman RL; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States.
  • Behenna DC; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States.
  • Boras B; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States.
  • Carelli J; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States.
  • Diehl W; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States.
  • Ferre RA; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States.
  • He YA; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States.
  • Hui A; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States.
  • Huang B; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States.
  • Huser N; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States.
  • Jones R; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States.
  • Kephart SE; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States.
  • Lapek J; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States.
  • McTigue M; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States.
  • Miller N; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States.
  • Murray BW; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States.
  • Nagata A; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States.
  • Nguyen L; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States.
  • Niessen S; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States.
  • Ninkovic S; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States.
  • O'Doherty I; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States.
  • Ornelas MA; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States.
  • Solowiej J; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States.
  • Sutton SC; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States.
  • Tran K; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States.
  • Tseng E; Pfizer Global Research and Development, Eastern Point Road, Groton, Connecticut 06340, United States.
  • Visswanathan R; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States.
  • Xu M; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States.
  • Zehnder L; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States.
  • Zhang Q; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States.
  • Zhang C; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States.
  • Dann S; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, California 92121, United States.
J Med Chem ; 64(13): 9056-9077, 2021 07 08.
Article em En | MEDLINE | ID: mdl-34110834
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inibidores de Proteínas Quinases / Descoberta de Drogas / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inibidores de Proteínas Quinases / Descoberta de Drogas / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos