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A first-in-class anticancer dual HDAC2/FAK inhibitors bearing hydroxamates/benzamides capped by pyridinyl-1,2,4-triazoles.
Mustafa, Muhamad; Abd El-Hafeez, Amer Ali; Abdelhamid, Dalia; Katkar, Gajanan D; Mostafa, Yaser A; Ghosh, Pradipta; Hayallah, Alaa M; Abuo-Rahma, Gamal El-Din A.
Afiliação
  • Mustafa M; Department of Medicinal Chemistry, Faculty of Pharmacy, Minia University, Minia, 61519, Egypt; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Deraya University, Minia, Egypt.
  • Abd El-Hafeez AA; Pharmacology and Experimental Oncology Unit, Cancer Biology Department, National Cancer Institute, Cairo University, Cairo, Egypt; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA. Electronic address: aam002@health.ucsd.edu.
  • Abdelhamid D; Department of Medicinal Chemistry, Faculty of Pharmacy, Minia University, Minia, 61519, Egypt.
  • Katkar GD; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA.
  • Mostafa YA; Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Assiut University, 71526, Egypt.
  • Ghosh P; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA; Department of Medicine, University of California San Diego, La Jolla, CA, USA; Moores Comprehensive Cancer Center, University of California San Diego, La Jolla, CA, USA; Veterans Affairs Medical Cen
  • Hayallah AM; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Deraya University, Minia, Egypt; Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Assiut University, 71526, Egypt; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Sphinx University, New Assiut, Egypt.
  • Abuo-Rahma GEA; Department of Medicinal Chemistry, Faculty of Pharmacy, Minia University, Minia, 61519, Egypt; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Deraya University, Minia, Egypt. Electronic address: gamal.aborahma@mu.edu.eg.
Eur J Med Chem ; 222: 113569, 2021 Oct 15.
Article em En | MEDLINE | ID: mdl-34111829
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Triazóis / Inibidores de Proteínas Quinases / Quinase 1 de Adesão Focal / Histona Desacetilase 2 / Inibidores de Histona Desacetilases / Antineoplásicos Limite: Humans Idioma: En Revista: Eur J Med Chem Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Egito País de publicação: França
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Triazóis / Inibidores de Proteínas Quinases / Quinase 1 de Adesão Focal / Histona Desacetilase 2 / Inibidores de Histona Desacetilases / Antineoplásicos Limite: Humans Idioma: En Revista: Eur J Med Chem Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Egito País de publicação: França