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Structure-based redesigning of pentoxifylline analogs against selective phosphodiesterases to modulate sperm functional competence for assisted reproductive technologies.
Satish, Mutyala; Kumari, Sandhya; Deeksha, Waghela; Abhishek, Suman; Nitin, Kulhar; Adiga, Satish Kumar; Hegde, Padmaraj; Dasappa, Jagadeesh Prasad; Kalthur, Guruprasad; Rajakumara, Eerappa.
Afiliação
  • Satish M; Macromolecular Structural Biology Lab, Department of Biotechnology, Indian Institute of Technology Hyderabad, Kandi, Sangareddy, Telangana, 502285, India.
  • Kumari S; Department of Clinical Embryology, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, 576104, India.
  • Deeksha W; Macromolecular Structural Biology Lab, Department of Biotechnology, Indian Institute of Technology Hyderabad, Kandi, Sangareddy, Telangana, 502285, India.
  • Abhishek S; Macromolecular Structural Biology Lab, Department of Biotechnology, Indian Institute of Technology Hyderabad, Kandi, Sangareddy, Telangana, 502285, India.
  • Nitin K; Macromolecular Structural Biology Lab, Department of Biotechnology, Indian Institute of Technology Hyderabad, Kandi, Sangareddy, Telangana, 502285, India.
  • Adiga SK; Department of Clinical Embryology, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, 576104, India.
  • Hegde P; Department of Urology, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, 576104, India.
  • Dasappa JP; Department of Chemistry, Mangalore University, Mangalagangothri, Karnataka, 574199, India.
  • Kalthur G; Department of Clinical Embryology, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, 576104, India. guru.kalthur@manipal.edu.
  • Rajakumara E; Macromolecular Structural Biology Lab, Department of Biotechnology, Indian Institute of Technology Hyderabad, Kandi, Sangareddy, Telangana, 502285, India. eraj@bt.iith.ac.in.
Sci Rep ; 11(1): 12293, 2021 06 10.
Article em En | MEDLINE | ID: mdl-34112881
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pentoxifilina / Espermatozoides / Diester Fosfórico Hidrolases / Astenozoospermia Limite: Humans / Male Idioma: En Revista: Sci Rep Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Índia País de publicação: Reino Unido
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pentoxifilina / Espermatozoides / Diester Fosfórico Hidrolases / Astenozoospermia Limite: Humans / Male Idioma: En Revista: Sci Rep Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Índia País de publicação: Reino Unido