[Metabolic hepatic steatosis associated with obesity in adults living in Burkina Faso]. / La stéatose hépatique métabolique liée à l´obésité chez l´adulte Burkinabè.

ABSTRACT

INTRODUCTION: is metabolic steatopathy a public health priority in Africa? The purpose of this study was to investigate the epidemiological factors and manifestations of liver involvement (biological abnormalities and steatosis on ultrasound) associated with metabolic syndrome (MS) in adults followed up on an ambulatory basis. METHODS: we conducted a cross-sectional and multicenter study based on longitudinal follow-up of patients in the city of Ouagadougou from March 2015 to August 2019. All patients with MS according to Harmonized Guidelines™ for sub-Saharan Africa were enrolled. RESULTS: MS rate was 15.74%. Recruitment of patients was 3.8 times faster in the last year. The majority of patients were women (57.04); the average age of patients was 44.69 years. Overweight and obesity accounted for 87.32%. MS components included dyslipidemia (64.79%), hyperglycemia (49.30%), PAH (45.07%), mean waist size (men 98.68 cm; women 101.13 cm). B virus infection was associated with MS in 19.01% of cases and HIV was associated with MS in 1.40% of cases. One female patient had polycystic ovary syndrome (PCOS). Patients on traditional therapy accounted for 14.08%. Transaminase levels were normal in 73.94% of cases. Hepatic steatosis on ultrasound were found in 71.13% of cases. Fibroscan® was performed in 40-42% cases. Fibroscan® results were discordant with ultrasound results in 56.14% of cases. CONCLUSION: this study highlights the importance of fighting against obesity (in particular obesity in women) in reducing MS and its components. A better accessibility to Fibroscan® could improve management of patients in Burkina Faso.