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Co-occurring gain-of-function mutations in HER2 and HER3 modulate HER2/HER3 activation, oncogenesis, and HER2 inhibitor sensitivity.
Hanker, Ariella B; Brown, Benjamin P; Meiler, Jens; Marín, Arnaldo; Jayanthan, Harikrishna S; Ye, Dan; Lin, Chang-Ching; Akamatsu, Hiroaki; Lee, Kyung-Min; Chatterjee, Sumanta; Sudhan, Dhivya R; Servetto, Alberto; Brewer, Monica Red; Koch, James P; Sheehan, Jonathan H; He, Jie; Lalani, Alshad S; Arteaga, Carlos L.
Afiliação
  • Hanker AB; UTSW Simmons Comprehensive Cancer Center, Dallas, 5323 Harry Hines Boulevard, TX 75390, USA; Department of Internal Medicine, UT Southwestern Medical Center, Dallas, TX 75390, USA. Electronic address: ariella.hanker@utsouthwestern.edu.
  • Brown BP; Chemical and Physical Biology Program, Center for Structural Biology, and Medical Scientist Training Program, Vanderbilt University, Nashville, TN 37240, USA.
  • Meiler J; Department of Chemistry and Center for Structural Biology, Vanderbilt University, Nashville, TN 37240, USA; Institute for Drug Discovery, Leipzig University Medical School, Leipzig, SAC 04103, Germany.
  • Marín A; UTSW Simmons Comprehensive Cancer Center, Dallas, 5323 Harry Hines Boulevard, TX 75390, USA; Doctoral Program in Medical Sciences, Faculty of Medicine, University of Chile, Santiago 8380453, Chile.
  • Jayanthan HS; Department of Chemistry and Center for Structural Biology, Vanderbilt University, Nashville, TN 37240, USA.
  • Ye D; UTSW Simmons Comprehensive Cancer Center, Dallas, 5323 Harry Hines Boulevard, TX 75390, USA.
  • Lin CC; UTSW Simmons Comprehensive Cancer Center, Dallas, 5323 Harry Hines Boulevard, TX 75390, USA.
  • Akamatsu H; UTSW Simmons Comprehensive Cancer Center, Dallas, 5323 Harry Hines Boulevard, TX 75390, USA.
  • Lee KM; UTSW Simmons Comprehensive Cancer Center, Dallas, 5323 Harry Hines Boulevard, TX 75390, USA; Department of Life Sciences, College of Natural Science, Hanyang University, Seoul 04736, Republic of Korea.
  • Chatterjee S; UTSW Simmons Comprehensive Cancer Center, Dallas, 5323 Harry Hines Boulevard, TX 75390, USA.
  • Sudhan DR; UTSW Simmons Comprehensive Cancer Center, Dallas, 5323 Harry Hines Boulevard, TX 75390, USA.
  • Servetto A; UTSW Simmons Comprehensive Cancer Center, Dallas, 5323 Harry Hines Boulevard, TX 75390, USA.
  • Brewer MR; Department of Chemistry and Center for Structural Biology, Vanderbilt University, Nashville, TN 37240, USA.
  • Koch JP; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
  • Sheehan JH; Division of Infectious Diseases, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.
  • He J; Foundation Medicine, Cambridge, MA 02141, USA.
  • Lalani AS; Puma Biotechnology, Inc., Los Angeles, CA 90024, USA.
  • Arteaga CL; UTSW Simmons Comprehensive Cancer Center, Dallas, 5323 Harry Hines Boulevard, TX 75390, USA; Department of Internal Medicine, UT Southwestern Medical Center, Dallas, TX 75390, USA.
Cancer Cell ; 39(8): 1099-1114.e8, 2021 08 09.
Article em En | MEDLINE | ID: mdl-34171264
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Quinolinas / Neoplasias da Mama / Receptor ErbB-2 / Receptor ErbB-3 / Mutação com Ganho de Função Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Cancer Cell Assunto da revista: NEOPLASIAS Ano de publicação: 2021 Tipo de documento: Article País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
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XML
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Quinolinas / Neoplasias da Mama / Receptor ErbB-2 / Receptor ErbB-3 / Mutação com Ganho de Função Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Cancer Cell Assunto da revista: NEOPLASIAS Ano de publicação: 2021 Tipo de documento: Article País de publicação: Estados Unidos