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Real-time Alerting System for COVID-19 Using Wearable Data.
Alavi, Arash; Bogu, Gireesh K; Wang, Meng; Rangan, Ekanath Srihari; Brooks, Andrew W; Wang, Qiwen; Higgs, Emily; Celli, Alessandra; Mishra, Tejaswini; Metwally, Ahmed A; Cha, Kexin; Knowles, Peter; Alavi, Amir A; Bhasin, Rajat; Panchamukhi, Shrinivas; Celis, Diego; Aditya, Tagore; Honkala, Alexander; Rolnik, Benjamin; Hunting, Erika; Dagan-Rosenfeld, Orit; Chauhan, Arshdeep; Li, Jessi W; Li, Xiao; Bahmani, Amir; Snyder, Michael P.
Afiliação
  • Alavi A; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.
  • Bogu GK; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.
  • Wang M; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.
  • Rangan ES; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.
  • Brooks AW; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.
  • Wang Q; Department of Computer Science, Stanford University, Stanford, CA, USA.
  • Higgs E; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.
  • Celli A; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.
  • Mishra T; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.
  • Metwally AA; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.
  • Cha K; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.
  • Knowles P; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.
  • Alavi AA; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.
  • Bhasin R; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.
  • Panchamukhi S; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.
  • Celis D; Department of Computer Science, Stanford University, Stanford, CA, USA.
  • Aditya T; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.
  • Honkala A; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.
  • Rolnik B; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.
  • Hunting E; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.
  • Dagan-Rosenfeld O; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.
  • Chauhan A; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.
  • Li JW; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.
  • Li X; The Center for RNA Science and Therapeutics, Case Western University, Cleveland, OH, USA.
  • Bahmani A; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.
  • Snyder MP; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.
medRxiv ; 2021 Jun 21.
Article em En | MEDLINE | ID: mdl-34189532
ABSTRACT
Early detection of infectious disease is crucial for reducing transmission and facilitating early intervention. We built a real-time smartwatch-based alerting system for the detection of aberrant physiological and activity signals (e.g. resting heart rate, steps) associated with early infection onset at the individual level. Upon applying this system to a cohort of 3,246 participants, we found that alerts were generated for pre-symptomatic and asymptomatic COVID-19 infections in 78% of cases, and pre-symptomatic signals were observed a median of three days prior to symptom onset. Furthermore, by examining over 100,000 survey annotations, we found that other respiratory infections as well as events not associated with COVID-19 (e.g. stress, alcohol consumption, travel) could trigger alerts, albeit at a lower mean period (1.9 days) than those observed in the COVID-19 cases (4.3 days). Thus this system has potential both for advanced warning of COVID-19 as well as a general system for measuring health via detection of physiological shifts from personal baselines. The system is open-source and scalable to millions of users, offering a personal health monitoring system that can operate in real time on a global scale.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Screening_studies Idioma: En Revista: MedRxiv Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Screening_studies Idioma: En Revista: MedRxiv Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos