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[Systemic treatment of moderate/severe hidradenitis suppurativa]. / Systemische Therapie der mittelschweren/schweren Hidradenitis suppurativa.
Pinter, A; Mrowietz, U; Volz, T.
Afiliação
  • Pinter A; Klinik für Dermatologie, Venerologie und Allergologie, Universitätsklinikum Frankfurt am Main, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Deutschland. andreas.pinter@kgu.de.
  • Mrowietz U; Zentrum für entzündliche Hauterkrankungen, Klinik für Dermatologie, Campus Kiel, Universitätsklinikum Schleswig-Holstein, Kiel, Deutschland.
  • Volz T; Klinik und Poliklinik für Dermatologie und Allergologie am Biederstein, Klinikum rechts der Isar, Technische Universität München, München, Deutschland.
Hautarzt ; 72(8): 686-691, 2021 Aug.
Article em De | MEDLINE | ID: mdl-34189590
Systemic treatment together with radical surgical excision is the most important treatment option for all severity grades of hidradenitis suppurativa. Tetracycline in mild-to-moderate forms and clindamycin in combination with rifampicin in moderate-to-severe forms are guideline-compliant first-line therapy with a good clinical response. Other antibiotics such as ertepenem or multiple combinations are recommended as last-line therapy due to a lack of data. Success rate with dapsone and retinoids, on the other hand, are insufficient-only acitretin can be recommended on the basis of the available studies, but with limited success. With the TNF-alpha blocker adalimumab, an effective and safe long-term therapy is available-further biologics are in clinical trials and could significantly expand the treatment portfolio in the future.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Produtos Biológicos / Hidradenite Supurativa Tipo de estudo: Diagnostic_studies / Guideline Limite: Humans Idioma: De Revista: Hautarzt Ano de publicação: 2021 Tipo de documento: Article País de publicação: Alemanha

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Produtos Biológicos / Hidradenite Supurativa Tipo de estudo: Diagnostic_studies / Guideline Limite: Humans Idioma: De Revista: Hautarzt Ano de publicação: 2021 Tipo de documento: Article País de publicação: Alemanha