Informational parameters of nucleic acid and molecular evolution.
J Theor Biol
; 130(3): 351-61, 1988 Feb 07.
Article
em En
| MEDLINE
| ID: mdl-3419187
ABSTRACT
From the point of view of information theory, a statistical analysis of 2000 nucleic acid sequences (732 coding regions and 1177 non-coding regions) is given. The sequences are grouped into 20 categories. The probability-order-difference (POD) matrix is defined which is used to analyse the evolutionary distance of any two categories of sequences. The informational parameters D1, D2 and X = (1 + D1/D2)-1 and F are calculated for each sequence and averaged in each category. The statistical dependence of these parameters on molecular evolution is discussed. It is found that [X] is a good statistical quantity which describes the vocabulary compositions as well as the grammatical constructions of the genetic language. From the statistical analysis it is shown that [X] may play an important role in investigating the evolutionary level of nucleic acid molecules.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Ácidos Nucleicos
/
Evolução Biológica
/
Teoria da Informação
Idioma:
En
Revista:
J Theor Biol
Ano de publicação:
1988
Tipo de documento:
Article
País de afiliação:
China
País de publicação:
ENGLAND
/
ESCOCIA
/
GB
/
GREAT BRITAIN
/
INGLATERRA
/
REINO UNIDO
/
SCOTLAND
/
UK
/
UNITED KINGDOM