Therapy Induced Genome Chaos: A Novel Mechanism of Rapid Cancer Drug Resistance.

Ye, Jing Christine; Horne, Steve; Zhang, Jack Z; Jackson, Lauren; Heng, Henry H

Ye, Jing Christine; Horne, Steve; Zhang, Jack Z; Jackson, Lauren; Heng, Henry H.

Afiliação

Ye JC; The Division of Hematology/Oncology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, United States.
Horne S; Center for Molecular Medicine and Genomics, Wayne State University School of Medicine, Detroit, MI, United States.
Zhang JZ; Center for Molecular Medicine and Genomics, Wayne State University School of Medicine, Detroit, MI, United States.
Jackson L; Center for Molecular Medicine and Genomics, Wayne State University School of Medicine, Detroit, MI, United States.
Heng HH; Center for Molecular Medicine and Genomics, Wayne State University School of Medicine, Detroit, MI, United States.

Front Cell Dev Biol ; 9: 676344, 2021.

Article em En | MEDLINE | ID: mdl-34195196

Palavras-chave

adaptive therapy; drug resistance; genome architecture theory; genome reorganization; karyotype coding; non-clonal chromosome aberrations; polyploid giant cancer cells; two-phased cancer evolution

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Front Cell Dev Biol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Suíça

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