Exposure to ethanol leads to midfacial hypoplasia in a zebrafish model of FASD via indirect interactions with the Shh pathway.

Sidik, Alfire; Dixon, Groves; Buckley, Desire M; Kirby, Hannah G; Sun, Shuge; Eberhart, Johann K

Sidik, Alfire; Dixon, Groves; Buckley, Desire M; Kirby, Hannah G; Sun, Shuge; Eberhart, Johann K.

Afiliação

Sidik A; Department of Molecular Biosciences, Institute for Cellular and Molecular Biology, Institute for Neuroscience, Waggoner Center for Alcohol and Addiction Research, University of Texas at Austin, Austin, Texas, 78712, USA. alfire.sidik@gmail.com.
Dixon G; Department of Integrative Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, Texas, 78712, USA.
Buckley DM; Department of Molecular Biosciences, Institute for Cellular and Molecular Biology, Institute for Neuroscience, Waggoner Center for Alcohol and Addiction Research, University of Texas at Austin, Austin, Texas, 78712, USA.
Kirby HG; Department of Molecular Biosciences, Institute for Cellular and Molecular Biology, Institute for Neuroscience, Waggoner Center for Alcohol and Addiction Research, University of Texas at Austin, Austin, Texas, 78712, USA.
Sun S; Department of Molecular Biosciences, Institute for Cellular and Molecular Biology, Institute for Neuroscience, Waggoner Center for Alcohol and Addiction Research, University of Texas at Austin, Austin, Texas, 78712, USA.
Eberhart JK; Department of Molecular Biosciences, Institute for Cellular and Molecular Biology, Institute for Neuroscience, Waggoner Center for Alcohol and Addiction Research, University of Texas at Austin, Austin, Texas, 78712, USA.

BMC Biol ; 19(1): 134, 2021 07 01.

Article em En | MEDLINE | ID: mdl-34210294

Assuntos

Transtornos do Espectro Alcoólico Fetal; Peixe-Zebra; Animais; Polaridade Celular; Etanol/toxicidade; Feminino; Transtornos do Espectro Alcoólico Fetal/genética; Proteínas Hedgehog/genética; Humanos; Gravidez; Efeitos Tardios da Exposição Pré-Natal; Via de Sinalização Wnt; Peixe-Zebra/genética; Proteínas de Peixe-Zebra/genética

Palavras-chave

Convergent extension; Cyclopia; Ethanol; Fetal alcohol spectrum disorders (FASD); Gastrulation; Polarity; Sonic Hedgehog (Shh); Vangl2; Wnt/planar cell polarity (PCP) pathway

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peixe-Zebra / Transtornos do Espectro Alcoólico Fetal Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Pregnancy Idioma: En Revista: BMC Biol Assunto da revista: BIOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google