[Placental transfer of monoclonal antibodies: The example of anti-TNF alpha drugs]. / Le passage placentaire des anticorps monoclonaux : exemple des anti-TNF alpha.

Anti-TNF alpha monoclonal antibodies are used in the treatment of chronic inflammatory diseases, which commonly affect women of childbearing age. Due to their similar structure to native immunoglobulins, the evaluation of their placental transfer by a pharmacological approach of the mechanisms involved is an interesting source of information, useful to the risk-benefit assessment of drugs in pregnant women.