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The Psoriatic Nonlesional Skin: A Battlefield between Susceptibility and Protective Factors.
Kelemen, Evelyn; Bozó, Renáta; Groma, Gergely; Bata-Csörgo, Zsuzsanna; Kemény, Lajos; Danis, Judit; Széll, Márta.
Afiliação
  • Kelemen E; Department of Dermatology and Allergology, Faculty of Medicine, University of Szeged, Szeged, Hungary; Department of Medical Genetics, Faculty of Medicine, University of Szeged, Szeged, Hungary.
  • Bozó R; Department of Dermatology and Allergology, Faculty of Medicine, University of Szeged, Szeged, Hungary; Hungarian Centre of Excellence for Molecular Medicine, University of Szeged, Skin Research Group, Szeged, Hungary.
  • Groma G; Department of Dermatology and Allergology, Faculty of Medicine, University of Szeged, Szeged, Hungary; MTA-SZTE Dermatological Research Group, Eötvös Loránd Research Network, Szeged, Hungary.
  • Bata-Csörgo Z; Department of Dermatology and Allergology, Faculty of Medicine, University of Szeged, Szeged, Hungary; Hungarian Centre of Excellence for Molecular Medicine, University of Szeged, Skin Research Group, Szeged, Hungary; MTA-SZTE Dermatological Research Group, Eötvös Loránd Research Network, Szeged, Hu
  • Kemény L; Department of Dermatology and Allergology, Faculty of Medicine, University of Szeged, Szeged, Hungary; Hungarian Centre of Excellence for Molecular Medicine, University of Szeged, Skin Research Group, Szeged, Hungary; MTA-SZTE Dermatological Research Group, Eötvös Loránd Research Network, Szeged, Hu
  • Danis J; Department of Medical Genetics, Faculty of Medicine, University of Szeged, Szeged, Hungary; Hungarian Centre of Excellence for Molecular Medicine, University of Szeged, Skin Research Group, Szeged, Hungary; MTA-SZTE Dermatological Research Group, Eötvös Loránd Research Network, Szeged, Hungary. Elec
  • Széll M; Department of Medical Genetics, Faculty of Medicine, University of Szeged, Szeged, Hungary; MTA-SZTE Dermatological Research Group, Eötvös Loránd Research Network, Szeged, Hungary.
J Invest Dermatol ; 141(12): 2785-2790, 2021 12.
Article em En | MEDLINE | ID: mdl-34216605
In the last two decades, large-scale gene-expression studies on psoriatic skin samples revealed that even though nonlesional skin is macroscopically identical to healthy skin, it harbors several molecular differences. Originally, these molecular differences were thought to represent susceptibility factors for plaque formation. However, we review in this paper the several factors of immune regulation and structural alteration that are specific for the nonlesional skin and serve as protective factors by counteracting plaque formation and contributing to the maintenance of the nonlesional phenotype.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Psoríase / Pele Tipo de estudo: Etiology_studies Limite: Humans Idioma: En Revista: J Invest Dermatol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Hungria País de publicação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Psoríase / Pele Tipo de estudo: Etiology_studies Limite: Humans Idioma: En Revista: J Invest Dermatol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Hungria País de publicação: Estados Unidos