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RIPK1 activates distinct gasdermins in macrophages and neutrophils upon pathogen blockade of innate immune signaling.
Chen, Kaiwen W; Demarco, Benjamin; Ramos, Saray; Heilig, Rosalie; Goris, Michiel; Grayczyk, James P; Assenmacher, Charles-Antoine; Radaelli, Enrico; Joannas, Leonel D; Henao-Mejia, Jorge; Tacchini-Cottier, Fabienne; Brodsky, Igor E; Broz, Petr.
Afiliação
  • Chen KW; Department of Biochemistry, University of Lausanne, CH-1066 Epalinges, Switzerland; kaiwen.chen@nus.edu.sg petr.broz@unil.ch.
  • Demarco B; Immunology Translational Research Programme and Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117456.
  • Ramos S; Department of Biochemistry, University of Lausanne, CH-1066 Epalinges, Switzerland.
  • Heilig R; Department of Biochemistry, University of Lausanne, CH-1066 Epalinges, Switzerland.
  • Goris M; Department of Biochemistry, University of Lausanne, CH-1066 Epalinges, Switzerland.
  • Grayczyk JP; Department of Biochemistry, University of Lausanne, CH-1066 Epalinges, Switzerland.
  • Assenmacher CA; Department of Pathobiology, University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA 19104.
  • Radaelli E; Department of Pathobiology, University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA 19104.
  • Joannas LD; Department of Pathobiology, University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA 19104.
  • Henao-Mejia J; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104.
  • Tacchini-Cottier F; Institue for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104.
  • Brodsky IE; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104.
  • Broz P; Institue for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104.
Proc Natl Acad Sci U S A ; 118(28)2021 07 13.
Article em En | MEDLINE | ID: mdl-34260403
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Yersinia pseudotuberculosis / Transdução de Sinais / Proteína Serina-Treonina Quinases de Interação com Receptores / Imunidade Inata / Macrófagos / Proteínas de Neoplasias / Neutrófilos Limite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2021 Tipo de documento: Article País de publicação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Yersinia pseudotuberculosis / Transdução de Sinais / Proteína Serina-Treonina Quinases de Interação com Receptores / Imunidade Inata / Macrófagos / Proteínas de Neoplasias / Neutrófilos Limite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2021 Tipo de documento: Article País de publicação: Estados Unidos