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H2dpa derivatives containing pentadentate ligands: An acyclic adjuvant potentiates meropenem activity in vitro and in vivo against metallo-ß-lactamase-producing Enterobacterales.
Chen, Fangfang; Bai, Mengmeng; Liu, Wentian; Kong, Hongtao; Zhang, Tingting; Yao, Hong; Zhang, En; Du, Juan; Qin, Shangshang.
Afiliação
  • Chen F; School of Pharmaceutical Sciences, Institute of Drug Discovery and Development, Key Laboratory of Advanced Pharmaceutical Technology, Ministry of Education of China, Zhengzhou University, Zhengzhou, 450001, PR China.
  • Bai M; School of Pharmaceutical Sciences, Institute of Drug Discovery and Development, Key Laboratory of Advanced Pharmaceutical Technology, Ministry of Education of China, Zhengzhou University, Zhengzhou, 450001, PR China.
  • Liu W; School of Pharmaceutical Sciences, Institute of Drug Discovery and Development, Key Laboratory of Advanced Pharmaceutical Technology, Ministry of Education of China, Zhengzhou University, Zhengzhou, 450001, PR China.
  • Kong H; School of Pharmaceutical Sciences, Institute of Drug Discovery and Development, Key Laboratory of Advanced Pharmaceutical Technology, Ministry of Education of China, Zhengzhou University, Zhengzhou, 450001, PR China.
  • Zhang T; School of Pharmaceutical Sciences, Institute of Drug Discovery and Development, Key Laboratory of Advanced Pharmaceutical Technology, Ministry of Education of China, Zhengzhou University, Zhengzhou, 450001, PR China.
  • Yao H; College of Veterinary Medicine, Henan Agricultural University, Zhengzhou, 450046, PR China.
  • Zhang E; School of Pharmaceutical Sciences, Institute of Drug Discovery and Development, Key Laboratory of Advanced Pharmaceutical Technology, Ministry of Education of China, Zhengzhou University, Zhengzhou, 450001, PR China. Electronic address: zhangen@zzu.edu.cn.
  • Du J; School of Pharmaceutical Sciences, Institute of Drug Discovery and Development, Key Laboratory of Advanced Pharmaceutical Technology, Ministry of Education of China, Zhengzhou University, Zhengzhou, 450001, PR China. Electronic address: dujuan2004@zzu.edu.cn.
  • Qin S; School of Pharmaceutical Sciences, Institute of Drug Discovery and Development, Key Laboratory of Advanced Pharmaceutical Technology, Ministry of Education of China, Zhengzhou University, Zhengzhou, 450001, PR China. Electronic address: qinshangshang@126.com.
Eur J Med Chem ; 224: 113702, 2021 Nov 15.
Article em En | MEDLINE | ID: mdl-34303873
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pseudomonas aeruginosa / Beta-Lactamases / Enterobacteriaceae / Inibidores de beta-Lactamases / Meropeném / Antibacterianos Limite: Animals Idioma: En Revista: Eur J Med Chem Ano de publicação: 2021 Tipo de documento: Article País de publicação: França
Texto completo
Adicionar na Minha BVS
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PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pseudomonas aeruginosa / Beta-Lactamases / Enterobacteriaceae / Inibidores de beta-Lactamases / Meropeném / Antibacterianos Limite: Animals Idioma: En Revista: Eur J Med Chem Ano de publicação: 2021 Tipo de documento: Article País de publicação: França