In-Silico analysis reveals lower transcription efficiency of C241T variant of SARS-CoV-2 with host replication factors MADP1 and hnRNP-1.

Chaudhari, Armi; Chaudhari, Minal; Mahera, Sapna; Saiyed, Zuber; Nathani, Neelam M; Shukla, Shantanu; Patel, Dhaval; Patel, Chirag; Joshi, Madhvi; Joshi, Chaitanya G

Chaudhari, Armi; Chaudhari, Minal; Mahera, Sapna; Saiyed, Zuber; Nathani, Neelam M; Shukla, Shantanu; Patel, Dhaval; Patel, Chirag; Joshi, Madhvi; Joshi, Chaitanya G.

Afiliação

Chaudhari A; Gujarat Biotechnology Research Centre (GBRC), Sector- 11, Gandhinagar - 382011, Gujarat, India.
Chaudhari M; Gujarat Biotechnology Research Centre (GBRC), Sector- 11, Gandhinagar - 382011, Gujarat, India.
Mahera S; Gujarat Biotechnology Research Centre (GBRC), Sector- 11, Gandhinagar - 382011, Gujarat, India.
Saiyed Z; Gujarat Biotechnology Research Centre (GBRC), Sector- 11, Gandhinagar - 382011, Gujarat, India.
Nathani NM; Gujarat Biotechnology Research Centre (GBRC), Sector- 11, Gandhinagar - 382011, Gujarat, India.
Shukla S; Genome Science and Technology, The University of Tennessee, Knoxville, TN - 37996, United States.
Patel D; Department of Bioinformatics and Structural Biology, Indian Institute of Advanced Research, Gandhinagar, 382426, Gujarat, India.
Patel C; Department of Botany, Bioinformatics and Climate Change Impacts Management, University School of Sciences, Gujarat University, Ahmedabad, 380009, India.
Joshi M; Gujarat Biotechnology Research Centre (GBRC), Sector- 11, Gandhinagar - 382011, Gujarat, India.
Joshi CG; Gujarat Biotechnology Research Centre (GBRC), Sector- 11, Gandhinagar - 382011, Gujarat, India.

Inform Med Unlocked ; 25: 100670, 2021.

Article em En | MEDLINE | ID: mdl-34307830

Palavras-chave

5'UTR; C241T; MADP1; MD simulations; MMPBSA; Protein-RNA complexes; SARS-CoV-2; hnRNP1

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Inform Med Unlocked Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Índia País de publicação: Reino Unido

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