Berberine Reverses Nitroglycerin Tolerance through Suppressing Protein Kinase C Alpha Activity in Vascular Smooth Muscle Cells.

Zhang, Huina; Dong, Jinghui; Lau, Chi-Wai; Huang, Yu

Zhang, Huina; Dong, Jinghui; Lau, Chi-Wai; Huang, Yu.

Afiliação

Zhang H; Beijing An Zhen Hospital, Capital Medical University; Key Laboratory of Upper Airway Dysfunction-related Cardiovascular Diseases, Beijing Institute of Heart Lung and Blood Vessel Disease, Beijing, 100029, China. whinnerzhn@126.com.
Dong J; Department of Physiology, Hebei Medical University, Hebei, 050017, China.
Lau CW; Shenzhen Research Institute, Heart and Vascular Institute, and Li Ka Shing Institute of Health Sciences, Chinese University of Hong Kong, Hong Kong, 999077, China.
Huang Y; Shenzhen Research Institute, Heart and Vascular Institute, and Li Ka Shing Institute of Health Sciences, Chinese University of Hong Kong, Hong Kong, 999077, China. yu-huang@cuhk.edu.hk.

Cardiovasc Drugs Ther ; 36(4): 633-643, 2022 08.

Article em En | MEDLINE | ID: mdl-34319490

Assuntos

Berberina; Nitroglicerina; Animais; Berberina/farmacologia; Músculo Liso Vascular; Nitroglicerina/farmacologia; Fosforilação; Proteína Quinase C-alfa; Ratos; Ratos Sprague-Dawley

Palavras-chave

Berberine; NTG tolerance; PKCα; Vascular smooth muscle cells

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Berberina / Nitroglicerina Limite: Animals Idioma: En Revista: Cardiovasc Drugs Ther Assunto da revista: ANGIOLOGIA / CARDIOLOGIA / TERAPIA POR MEDICAMENTOS Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China País de publicação: Estados Unidos

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