Your browser doesn't support javascript.
loading
Long-Term Outcomes and Health-Related Quality of Life in a Swiss Patient Group with Esophageal Atresia.
di Natale, Anthony; Brestel, Jessica; Mauracher, Andrea Alexis; Tharakan, Sasha Job; Meuli, Martin; Möhrlen, Ueli; Subotic, Ulrike.
Afiliação
  • di Natale A; Department of Pediatric Surgery, University Children's Hospital Zurich, Zurich, Switzerland.
  • Brestel J; Department of Pediatric Surgery, University Children's Hospital Zurich, Zurich, Switzerland.
  • Mauracher AA; Division of Immunology, University Children's Hospital Zurich, Zurich, Switzerland.
  • Tharakan SJ; Department of Pediatric Surgery, University Children's Hospital Zurich, Zurich, Switzerland.
  • Meuli M; Department of Pediatric Surgery, University Children's Hospital Zurich, Zurich, Switzerland.
  • Möhrlen U; Department of Pediatric Surgery, University Children's Hospital Zurich, Zurich, Switzerland.
  • Subotic U; Department of Pediatric Surgery, University Children's Hospital Zurich, Zurich, Switzerland.
Eur J Pediatr Surg ; 32(4): 334-345, 2022 Aug.
Article em En | MEDLINE | ID: mdl-34327690
INTRODUCTION: Surgical treatment of esophageal atresia (EA) has markedly improved, allowing the focus to shift from short-term complications and mortality to long-term complications and quality of life. Health-related quality of life (HRQoL) is variable and reported to range from reduced to unimpaired in patients with repaired EA. We assessed the HRQoL, determined the prevalence of long-term complications and their possible impact on the HRQoL in patients who had correction of EA in Switzerland. Further, we also investigated in the general well-being of their parents. MATERIALS AND METHODS: Patients with EA repair in Switzerland between 1985 and 2011 were enrolled. Long-term complications were assessed by enquiring disease-related symptoms, standardized clinical examinations, and analysis of radiographs. HRQoL was inquired using different validated questionnaires (KIDSCREEN-27, World Health Organization [WHO]-5, and Gastrointestinal Quality of Life Index [GIQLI]). Patients were grouped according to their age. In underage patients, general well-being of the parents was assessed using the WHO-5 questionnaire. RESULTS: Thirty patients were included with a mean age of 11.3 ± 5.7 years. Long-term complications were present in 63% of all patients. HRQoL in underage patients was comparable to the provided reference values and rated as good, while adult patients reported a reduced HRQoL. The presence of gastroesophageal reflux disease symptoms was associated with reduced HRQoL in underage patients. Parents of underage patients stated a good general well-being. CONCLUSION: Long-term complications among patients with repair of EA in Switzerland are common. HRQoL in underage patients is good and general well-being of their parents is unimpaired. Adult patients reported a reduced HRQoL, consistent with other reports. As long-term complications may manifest only later in life, a structured follow-up of patients with an EA repair during childhood and adolescence is needed.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Atresia Esofágica / Esofagoplastia Tipo de estudo: Qualitative_research / Risk_factors_studies Aspecto: Patient_preference Limite: Adolescent / Adult / Child / Child, preschool / Humans País/Região como assunto: Europa Idioma: En Revista: Eur J Pediatr Surg Assunto da revista: PEDIATRIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Suíça País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Atresia Esofágica / Esofagoplastia Tipo de estudo: Qualitative_research / Risk_factors_studies Aspecto: Patient_preference Limite: Adolescent / Adult / Child / Child, preschool / Humans País/Região como assunto: Europa Idioma: En Revista: Eur J Pediatr Surg Assunto da revista: PEDIATRIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Suíça País de publicação: Estados Unidos