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Targeting Notch Inhibitors to the Myeloma Bone Marrow Niche Decreases Tumor Growth and Bone Destruction without Gut Toxicity.
Sabol, Hayley M; Ferrari, Adam J; Adhikari, Manish; Amorim, Tânia; McAndrews, Kevin; Anderson, Judith; Vigolo, Michele; Lehal, Rajwinder; Cregor, Meloney; Khan, Sharmin; Cuevas, Pedro L; Helms, Jill A; Kurihara, Noriyoshi; Srinivasan, Venkat; Ebetino, Frank H; Boeckman, Robert K; Roodman, G David; Bellido, Teresita; Delgado-Calle, Jesus.
Afiliação
  • Sabol HM; Department of Physiology and Cell Biology, University of Arkansas for Medical Sciences, Little Rock, Arkansas.
  • Ferrari AJ; Department of Medicine, Hematology/Oncology, Indiana University School of Medicine, Indianapolis, Indiana.
  • Adhikari M; Department of Physiology and Cell Biology, University of Arkansas for Medical Sciences, Little Rock, Arkansas.
  • Amorim T; Department of Medicine, Hematology/Oncology, Indiana University School of Medicine, Indianapolis, Indiana.
  • McAndrews K; Department of Anatomy, Cell Biology & Physiology, Indiana University School of Medicine, Indianapolis, Indiana.
  • Anderson J; Department of Medicine, Hematology/Oncology, Indiana University School of Medicine, Indianapolis, Indiana.
  • Vigolo M; Cellestia Biotech, Basel, Switzerland.
  • Lehal R; Cellestia Biotech, Basel, Switzerland.
  • Cregor M; Department of Physiology and Cell Biology, University of Arkansas for Medical Sciences, Little Rock, Arkansas.
  • Khan S; Department of Physiology and Cell Biology, University of Arkansas for Medical Sciences, Little Rock, Arkansas.
  • Cuevas PL; Division of Plastic and Reconstructive Surgery, Department of Surgery, Stanford University School of Medicine, Palo Alto, California.
  • Helms JA; Division of Plastic and Reconstructive Surgery, Department of Surgery, Stanford University School of Medicine, Palo Alto, California.
  • Kurihara N; Department of Medicine, Hematology/Oncology, Indiana University School of Medicine, Indianapolis, Indiana.
  • Srinivasan V; Department of Chemistry, University of Rochester, Rochester, New York.
  • Ebetino FH; Department of Chemistry, University of Rochester, Rochester, New York.
  • Boeckman RK; Biovinc LLC, Pasadena, California.
  • Roodman GD; Department of Chemistry, University of Rochester, Rochester, New York.
  • Bellido T; Department of Medicine, Hematology/Oncology, Indiana University School of Medicine, Indianapolis, Indiana.
  • Delgado-Calle J; Roudebush VA Medical Center, Indianapolis, Indiana.
Cancer Res ; 81(19): 5102-5114, 2021 10 01.
Article em En | MEDLINE | ID: mdl-34348968

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osso e Ossos / Células da Medula Óssea / Receptores Notch / Mieloma Múltiplo Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Cancer Res Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osso e Ossos / Células da Medula Óssea / Receptores Notch / Mieloma Múltiplo Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Cancer Res Ano de publicação: 2021 Tipo de documento: Article