Human umbilical cord mesenchymal stem cells reduce oxidative damage and apoptosis in diabetic nephropathy by activating Nrf2.

Nie, Ping; Bai, Xue; Lou, Yan; Zhu, Yuexin; Jiang, Shan; Zhang, Lina; Tian, Na; Luo, Ping; Li, Bing

Nie, Ping; Bai, Xue; Lou, Yan; Zhu, Yuexin; Jiang, Shan; Zhang, Lina; Tian, Na; Luo, Ping; Li, Bing.

Afiliação

Nie P; Department of Nephropathy, The Second Hospital of Jilin University, Changchun, Jilin Province, China.
Bai X; Department of Nephropathy, The Second Hospital of Jilin University, Changchun, Jilin Province, China.
Lou Y; Department of Nephropathy, The Second Hospital of Jilin University, Changchun, Jilin Province, China.
Zhu Y; Department of Nephropathy, The Second Hospital of Jilin University, Changchun, Jilin Province, China.
Jiang S; Department of Nephropathy, The Second Hospital of Jilin University, Changchun, Jilin Province, China.
Zhang L; Research and Development Department, Jilin Tuohua Biotechnology Co., Ltd., Changchun, Jilin Province, China.
Tian N; Research and Development Department, Jilin Tuohua Biotechnology Co., Ltd., Changchun, Jilin Province, China.
Luo P; Department of Nephropathy, The Second Hospital of Jilin University, Changchun, Jilin Province, China. luopingjen@163.com.
Li B; Department of Nephropathy, The Second Hospital of Jilin University, Changchun, Jilin Province, China. li_bing2020@jlu.edu.cn.

Stem Cell Res Ther ; 12(1): 450, 2021 08 11.

Article em En | MEDLINE | ID: mdl-34380544

Assuntos

Diabetes Mellitus Tipo 2; Nefropatias Diabéticas; Células-Tronco Mesenquimais; Animais; Apoptose; Diabetes Mellitus Tipo 2/metabolismo; Diabetes Mellitus Tipo 2/terapia; Nefropatias Diabéticas/genética; Nefropatias Diabéticas/metabolismo; Nefropatias Diabéticas/terapia; Humanos; Células-Tronco Mesenquimais/metabolismo; Fator 2 Relacionado a NF-E2/genética; Fator 2 Relacionado a NF-E2/metabolismo; Estresse Oxidativo; Ratos; Cordão Umbilical/metabolismo

Palavras-chave

Apoptosis; Diabetic nephropathy; Mesenchymal stem cell; Nrf2; Oxidative damage

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Diabetes Mellitus Tipo 2 / Nefropatias Diabéticas / Células-Tronco Mesenquimais Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Stem Cell Res Ther Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China País de publicação: Reino Unido

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