Autophagy Inhibition Plays a Protective Role in Ferroptosis Induced by Alcohol via the p62-Keap1-Nrf2 Pathway.

Zhao, Yanan; Lu, Jing; Mao, Ankang; Zhang, Ranran; Guan, Shuang

Zhao, Yanan; Lu, Jing; Mao, Ankang; Zhang, Ranran; Guan, Shuang.

Afiliação

Zhao Y; College of Food Science and Engineering, Jilin University, Changchun, Jilin 130062, People's Republic of China.
Lu J; College of Food Science and Engineering, Jilin University, Changchun, Jilin 130062, People's Republic of China.
Mao A; Key Laboratory of Zoonosis, Ministry of Education College of Veterinary Medicine, Jilin University, Changchun, Jilin 130062, People's Republic of China.
Zhang R; College of Food Science and Engineering, Jilin University, Changchun, Jilin 130062, People's Republic of China.
Guan S; College of Food Science and Engineering, Jilin University, Changchun, Jilin 130062, People's Republic of China.

J Agric Food Chem ; 69(33): 9671-9683, 2021 Aug 25.

Article em En | MEDLINE | ID: mdl-34388345

Assuntos

Ferroptose; Fator 2 Relacionado a NF-E2; Autofagia; Células Hep G2; Humanos; Proteína 1 Associada a ECH Semelhante a Kelch/genética; Proteína 1 Associada a ECH Semelhante a Kelch/metabolismo; Fator 2 Relacionado a NF-E2/genética; Fator 2 Relacionado a NF-E2/metabolismo; Estresse Oxidativo; Proteína Sequestossoma-1/genética; Proteína Sequestossoma-1/metabolismo; Transdução de Sinais

Palavras-chave

HepG2; alcohol; autophagy; ferroptosis; p62−Keap1−Nrf2

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fator 2 Relacionado a NF-E2 / Ferroptose Tipo de estudo: Guideline Limite: Humans Idioma: En Revista: J Agric Food Chem Ano de publicação: 2021 Tipo de documento: Article País de publicação: Estados Unidos

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