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Targeting ROS-AMPK pathway by multiaction Platinum(IV) prodrugs containing hypolipidemic drug bezafibrate.
Qiao, Xin; Gao, Yu-Yang; Zheng, Li-Xia; Ding, Xiao-Jing; Xu, Ling-Wen; Hu, Juan-Juan; Gao, Wei-Zhen; Xu, Jing-Yuan.
Afiliação
  • Qiao X; Department of Chemical Biology and Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics, School of Pharmacy, Tianjin Medical University, Tianjin, 300070, China.
  • Gao YY; Department of Chemical Biology and Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics, School of Pharmacy, Tianjin Medical University, Tianjin, 300070, China.
  • Zheng LX; Department of Chemical Biology and Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics, School of Pharmacy, Tianjin Medical University, Tianjin, 300070, China.
  • Ding XJ; Department of Chemical Biology and Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics, School of Pharmacy, Tianjin Medical University, Tianjin, 300070, China.
  • Xu LW; Department of Chemical Biology and Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics, School of Pharmacy, Tianjin Medical University, Tianjin, 300070, China.
  • Hu JJ; Department of Chemical Biology and Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics, School of Pharmacy, Tianjin Medical University, Tianjin, 300070, China.
  • Gao WZ; Department of Chemical Biology and Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics, School of Pharmacy, Tianjin Medical University, Tianjin, 300070, China; Department of Pharmacology, School of Basic Medical Sciences, Tianjin Medical University, T
  • Xu JY; Department of Chemical Biology and Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics, School of Pharmacy, Tianjin Medical University, Tianjin, 300070, China. Electronic address: xujingyuan@tmu.edu.cn.
Eur J Med Chem ; 223: 113730, 2021 Nov 05.
Article em En | MEDLINE | ID: mdl-34388483
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Platina / Bezafibrato / Pró-Fármacos / Espécies Reativas de Oxigênio / Proteínas Quinases Ativadas por AMP / Hipolipemiantes Limite: Humans Idioma: En Revista: Eur J Med Chem Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China País de publicação: França
Texto completo
Adicionar na Minha BVS
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Platina / Bezafibrato / Pró-Fármacos / Espécies Reativas de Oxigênio / Proteínas Quinases Ativadas por AMP / Hipolipemiantes Limite: Humans Idioma: En Revista: Eur J Med Chem Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China País de publicação: França