Nerolidol inhibits proliferation of leiomyoma cells via reactive oxygen species-induced DNA damage and downregulation of the ATM/Akt pathway.

Dong, Jun-Ren; Chang, Wen-Wei; Chen, Shih-Ming

Dong, Jun-Ren; Chang, Wen-Wei; Chen, Shih-Ming.

Afiliação

Dong JR; School of Biomedical Sciences, Chung Shan Medical University, Taichung, 40201, Taiwan. Electronic address: s8907001166@gmail.com.
Chang WW; School of Biomedical Sciences, Chung Shan Medical University, Taichung, 40201, Taiwan; Department of Medical Research, Chung Shan Medical University Hospital, Taichung, 40201, Taiwan. Electronic address: changww@csmu.edu.tw.
Chen SM; Bachelor Program in Health Care and Social Work for Indigenous Students, Providence University, Taichung, 43301, Taiwan. Electronic address: big32762992@pu.edu.tw.

Phytochemistry ; 191: 112901, 2021 Nov.

Article em En | MEDLINE | ID: mdl-34388663

Assuntos

Leiomioma; Sesquiterpenos; Apoptose; Linhagem Celular Tumoral; Proliferação de Células; Dano ao DNA; Regulação para Baixo; Proteínas Proto-Oncogênicas c-akt/metabolismo; Espécies Reativas de Oxigênio/metabolismo; Sesquiterpenos/farmacologia

Palavras-chave

ATM/Akt; Cancer cell biology; DNA damage; G1 cell cycle arrest; Nerolidol; Reactive oxygen species; Sequiterpene alcohol

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sesquiterpenos / Leiomioma Idioma: En Revista: Phytochemistry Ano de publicação: 2021 Tipo de documento: Article País de publicação: Reino Unido

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google