Six new cadinane-type sesquiterpenoids from the leaves of Chimonanthus nitens Oliv.
Fitoterapia
; 154: 105019, 2021 Oct.
Article
em En
| MEDLINE
| ID: mdl-34403777
ABSTRACT
Six new cadinane-type sesquiterpenoids, named Chimnitensin A-F (1-6) were isolated from the leaves of Chimonanthus nitens Oliv. Their structures were elucidated by comprehensive spectroscopic analyses and comparison with structurally related known analogues. In vitro MTT assay showed that all six compounds had cytotoxicity against two selected human breast cancer cell lines (MDA-MB-468 and MDA-MB-231), which indicate their potential of developing into anticancer drugs.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Calycanthaceae
/
Sesquiterpenos Policíclicos
/
Antineoplásicos Fitogênicos
Limite:
Humans
País/Região como assunto:
Asia
Idioma:
En
Revista:
Fitoterapia
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
China