Extensive phenotypic characterisation of a human TDP-43<sup>Q331K</sup> transgenic mouse model of amyotrophic lateral sclerosis (ALS).

Watkins, Jodie A; Alix, James J P; Shaw, Pamela J; Mead, Richard J

Extensive phenotypic characterisation of a human TDP-43^Q331K transgenic mouse model of amyotrophic lateral sclerosis (ALS).

Watkins, Jodie A; Alix, James J P; Shaw, Pamela J; Mead, Richard J.

Afiliação

Watkins JA; Sheffield Institute for Translational Neuroscience, Department of Neuroscience, School of Medicine, University of Sheffield, Sheffield, UK.
Alix JJP; Sheffield Institute for Translational Neuroscience, Department of Neuroscience, School of Medicine, University of Sheffield, Sheffield, UK.
Shaw PJ; Sheffield Institute for Translational Neuroscience, Department of Neuroscience, School of Medicine, University of Sheffield, Sheffield, UK.
Mead RJ; Sheffield Institute for Translational Neuroscience, Department of Neuroscience, School of Medicine, University of Sheffield, Sheffield, UK. r.j.mead@sheffield.ac.uk.

Sci Rep ; 11(1): 16659, 2021 08 17.

Article em En | MEDLINE | ID: mdl-34404845

Assuntos

Esclerose Lateral Amiotrófica/genética; Proteínas de Ligação a DNA/genética; Esclerose Lateral Amiotrófica/patologia; Animais; Modelos Animais de Doenças; Feminino; Humanos; Masculino; Camundongos Transgênicos; Mutação Puntual

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Ligação a DNA / Esclerose Lateral Amiotrófica Limite: Animals / Female / Humans / Male Idioma: En Revista: Sci Rep Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Reino Unido

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