Inhibitory effects of ultrasound irradiation on Staphylococcus epidermidis biofilm.
J Med Ultrason (2001)
; 48(4): 439-448, 2021 Oct.
Article
em En
| MEDLINE
| ID: mdl-34410547
ABSTRACT
PURPOSE:
We aimed to investigate whether low-intensity continuous and pulsed wave ultrasound (US) irradiation can inhibit the formation of Staphylococcus epidermidis biofilms, for potential application in the treatment of catheter-related bloodstream infections (CRBSI).METHODS:
S. epidermidis biofilms that formed on the bottom surfaces of 6-well plates were irradiated on the bottom surface using the sound cell incubator system for different intervals of time.RESULTS:
US irradiation with continuous waves for 24 h notably inhibited biofilm formation (p < 0.01), but the same US irradiation for 12 h had no remarkable effect. Further, double US irradiation with pulsed waves for 20 min inhibited biofilm formation by 33.6%, nearly two-fold more than single US irradiation, which reduced it by 17.9%.CONCLUSION:
US irradiation of a lower intensity (ISATA = 6-29 mW/cm2) than used in a previous study and lower than recommended by the Food and Drug Administration shows potential for preventing CRBSI caused by bacterial biofilms.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Infecções Estafilocócicas
/
Staphylococcus epidermidis
Limite:
Humans
Idioma:
En
Revista:
J Med Ultrason (2001)
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
Japão