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The antidepressant drug vilazodone is an allosteric inhibitor of the serotonin transporter.
Plenge, Per; Yang, Dongxue; Salomon, Kristine; Laursen, Louise; Kalenderoglou, Iris E; Newman, Amy H; Gouaux, Eric; Coleman, Jonathan A; Loland, Claus J.
Afiliação
  • Plenge P; Laboratory for Membrane Protein Dynamics. Department of Neuroscience, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Yang D; Vollum Institute, Oregon Health & Science University, Portland, OR, USA.
  • Salomon K; Laboratory for Membrane Protein Dynamics. Department of Neuroscience, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Laursen L; Laboratory for Membrane Protein Dynamics. Department of Neuroscience, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Kalenderoglou IE; Laboratory for Membrane Protein Dynamics. Department of Neuroscience, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Newman AH; Medicinal Chemistry Section, Molecular Targets and Medications Discovery Branch, National Institute on Drug Abuse - Intramural Research Program, National Institutes of Health, Baltimore, MD, USA.
  • Gouaux E; Vollum Institute, Oregon Health & Science University, Portland, OR, USA.
  • Coleman JA; Howard Hughes Medical Institute, Oregon Health & Science University, Portland, OR, USA.
  • Loland CJ; Vollum Institute, Oregon Health & Science University, Portland, OR, USA. coleman1@pitt.edu.
Nat Commun ; 12(1): 5063, 2021 08 20.
Article em En | MEDLINE | ID: mdl-34417466

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inibidores Seletivos de Recaptação de Serotonina / Proteínas da Membrana Plasmática de Transporte de Serotonina / Cloridrato de Vilazodona / Antidepressivos Limite: Animals / Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Dinamarca País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inibidores Seletivos de Recaptação de Serotonina / Proteínas da Membrana Plasmática de Transporte de Serotonina / Cloridrato de Vilazodona / Antidepressivos Limite: Animals / Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Dinamarca País de publicação: Reino Unido