A genome-wide association study of the frailty index highlights brain pathways in ageing.

Atkins, Janice L; Jylhävä, Juulia; Pedersen, Nancy L; Magnusson, Patrik K; Lu, Yi; Wang, Yunzhang; Hägg, Sara; Melzer, David; Williams, Dylan M; Pilling, Luke C

Atkins, Janice L; Jylhävä, Juulia; Pedersen, Nancy L; Magnusson, Patrik K; Lu, Yi; Wang, Yunzhang; Hägg, Sara; Melzer, David; Williams, Dylan M; Pilling, Luke C.

Afiliação

Atkins JL; Epidemiology and Public Health Group, University of Exeter Medical School, Exeter, UK.
Jylhävä J; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Pedersen NL; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Magnusson PK; Department of Psychology, University of Southern California, Los Angeles, CA, USA.
Lu Y; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Wang Y; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Hägg S; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Melzer D; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Williams DM; Epidemiology and Public Health Group, University of Exeter Medical School, Exeter, UK.
Pilling LC; Center on Aging, University of Connecticut, Farmington, CT, USA.

Aging Cell ; 20(9): e13459, 2021 09.

Article em En | MEDLINE | ID: mdl-34431594

Assuntos

Envelhecimento/genética; Encéfalo/metabolismo; Fragilidade/genética; Adulto; Idoso; Envelhecimento/metabolismo; Fragilidade/metabolismo; Estudo de Associação Genômica Ampla; Humanos; Pessoa de Meia-Idade; Gêmeos/genética

Palavras-chave

UK Biobank; ageing; frailty; frailty index; genetics

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Encéfalo / Envelhecimento / Fragilidade Tipo de estudo: Clinical_trials / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Humans / Middle aged Idioma: En Revista: Aging Cell Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Reino Unido

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