Double knockout of vitamin D receptor and its coactivator mediator complex subunit 1 unexpectedly enhances epidermal permeability barrier function in mice.

Zhang, Jing; Zhu, Qianyu; Zhang, Shuchang; Wu, Jiangmei; Huang, Junkai; Li, Mengyan; Wang, Xiaohua; Man, Mao-Qiang; Hu, Lizhi

Zhang, Jing; Zhu, Qianyu; Zhang, Shuchang; Wu, Jiangmei; Huang, Junkai; Li, Mengyan; Wang, Xiaohua; Man, Mao-Qiang; Hu, Lizhi.

Afiliação

Zhang J; Immunology Department, Key Laboratory of Immune Microenvironment and Disease (Ministry of Education), Tianjin Medical University, Tianjin 300070, China; Department of Pathogen Biology and Immunology, Basic Medical College, Tianjin Medical University, Tianjin 300070, China.
Zhu Q; Immunology Department, Key Laboratory of Immune Microenvironment and Disease (Ministry of Education), Tianjin Medical University, Tianjin 300070, China; Department of Pathogen Biology and Immunology, Basic Medical College, Tianjin Medical University, Tianjin 300070, China.
Zhang S; Immunology Department, Key Laboratory of Immune Microenvironment and Disease (Ministry of Education), Tianjin Medical University, Tianjin 300070, China; Department of Pathogen Biology and Immunology, Basic Medical College, Tianjin Medical University, Tianjin 300070, China.
Wu J; Immunology Department, Key Laboratory of Immune Microenvironment and Disease (Ministry of Education), Tianjin Medical University, Tianjin 300070, China; Department of Pathogen Biology and Immunology, Basic Medical College, Tianjin Medical University, Tianjin 300070, China.
Huang J; Immunology Department, Key Laboratory of Immune Microenvironment and Disease (Ministry of Education), Tianjin Medical University, Tianjin 300070, China; Department of Pathogen Biology and Immunology, Basic Medical College, Tianjin Medical University, Tianjin 300070, China.
Li M; Immunology Department, Key Laboratory of Immune Microenvironment and Disease (Ministry of Education), Tianjin Medical University, Tianjin 300070, China; Department of Pathogen Biology and Immunology, Basic Medical College, Tianjin Medical University, Tianjin 300070, China.
Wang X; Dermatology Hospital, Southern Medical University, Guangzhou 510091, China.
Man MQ; Dermatology Hospital, Southern Medical University, Guangzhou 510091, China.
Hu L; Immunology Department, Key Laboratory of Immune Microenvironment and Disease (Ministry of Education), Tianjin Medical University, Tianjin 300070, China; Department of Pathogen Biology and Immunology, Basic Medical College, Tianjin Medical University, Tianjin 300070, China. Electronic address: lizhih

Biochim Biophys Acta Mol Cell Res ; 1868(12): 119131, 2021 11.

Article em En | MEDLINE | ID: mdl-34453978

Assuntos

Epiderme/metabolismo; Subunidade 1 do Complexo Mediador/genética; Receptores de Calcitriol/genética; Animais; Diferenciação Celular; Ceramidas/metabolismo; Queratinócitos/citologia; Queratinócitos/metabolismo; Mutação com Perda de Função; Subunidade 1 do Complexo Mediador/metabolismo; Camundongos; Receptores de Calcitriol/metabolismo

Palavras-chave

Differentiation; Lipid synthesis; Mediator complex subunit 1; Permeability barrier function; Vitamin d receptor

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores de Calcitriol / Epiderme / Subunidade 1 do Complexo Mediador Limite: Animals Idioma: En Revista: Biochim Biophys Acta Mol Cell Res Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China País de publicação: Holanda

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