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Pantoprazole ameliorates liver fibrosis and suppresses hepatic stellate cell activation in bile duct ligation rats by promoting YAP degradation.
Lu, Zhen-Ning; Niu, Wei-Xiao; Zhang, Na; Ge, Mao-Xu; Bao, Yun-Yang; Ren, Yu; Guo, Xiu-Li; He, Hong-Wei.
Afiliação
  • Lu ZN; Key Laboratory of Biotechnology of Antibiotics, the National Health and Family Planning Commission (NHFPC), Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100050, China.
  • Niu WX; Key Laboratory of Biotechnology of Antibiotics, the National Health and Family Planning Commission (NHFPC), Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100050, China.
  • Zhang N; Key Laboratory of Biotechnology of Antibiotics, the National Health and Family Planning Commission (NHFPC), Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100050, China.
  • Ge MX; Department of Pharmacy, Qilu Hospital of Shandong University, Jinan, 250012, China.
  • Bao YY; Key Laboratory of Biotechnology of Antibiotics, the National Health and Family Planning Commission (NHFPC), Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100050, China.
  • Ren Y; Key Laboratory of Biotechnology of Antibiotics, the National Health and Family Planning Commission (NHFPC), Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100050, China.
  • Guo XL; Department of Pharmacology, Key Laboratory of Chemical Biology (Ministry of Education), Drug Screening Unit Platform, School of Pharmaceutical Sciences, Shandong University, Jinan, 250012, China. guoxl@sdu.edu.cn.
  • He HW; Key Laboratory of Biotechnology of Antibiotics, the National Health and Family Planning Commission (NHFPC), Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100050, China. hehwei@imb.pumc.edu.cn.
Acta Pharmacol Sin ; 42(11): 1808-1820, 2021 11.
Article em En | MEDLINE | ID: mdl-34465912

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ductos Biliares / Células Estreladas do Fígado / Proteólise / Pantoprazol / Proteínas de Sinalização YAP / Cirrose Hepática Limite: Animals / Humans / Male Idioma: En Revista: Acta Pharmacol Sin Assunto da revista: FARMACOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ductos Biliares / Células Estreladas do Fígado / Proteólise / Pantoprazol / Proteínas de Sinalização YAP / Cirrose Hepática Limite: Animals / Humans / Male Idioma: En Revista: Acta Pharmacol Sin Assunto da revista: FARMACOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China