Long non-coding RNA RP11-490M8.1 inhibits lipopolysaccharide-induced pyroptosis of human umbilical vein endothelial cells via the TLR4/NF-&#954;B pathway.

Liu, Xue-Hui; Wu, Li-Mei; Wang, Jia-Li; Dong, Xian-Hui; Zhang, Shun-Chi; Li, Xue-Heng; Xu, Hui; Liu, Da-Bin; Li, Zhi-Hai; Liu, Zhe-Ming; Wu, Shao-Guo; Hu, Yan-Wei

Long non-coding RNA RP11-490M8.1 inhibits lipopolysaccharide-induced pyroptosis of human umbilical vein endothelial cells via the TLR4/NF-κB pathway.

Liu, Xue-Hui; Wu, Li-Mei; Wang, Jia-Li; Dong, Xian-Hui; Zhang, Shun-Chi; Li, Xue-Heng; Xu, Hui; Liu, Da-Bin; Li, Zhi-Hai; Liu, Zhe-Ming; Wu, Shao-Guo; Hu, Yan-Wei.

Afiliação

Liu XH; Department of Laboratory Medicine Center, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong 510515, China; Department of Clinical Laboratory, Guangzhou Twelfth People's Hospital, Guangzhou, Guangdong 510620, China.
Wu LM; Department of Clinical Laboratory, Guangzhou Twelfth People's Hospital, Guangzhou, Guangdong 510620, China.
Wang JL; Department of Blood Transfusion, Linyi People's Hospital of Shandong Province, Linyi, ShanDong 276000, China.
Dong XH; Department of Clinical Laboratory, Guangzhou Women and Children's Medical Center, Guangzhou, Guangdong 510623, China.
Zhang SC; Department of Clinical Laboratory, Guangzhou Twelfth People's Hospital, Guangzhou, Guangdong 510620, China.
Li XH; Department of Laboratory Medicine Center, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong 510515, China.
Xu H; Traditional Chinese Medical Hospital of Qingyuan, Qingyuan, Guangdong 511500, China.
Liu DB; Department of Clinical Laboratory, Guangzhou Twelfth People's Hospital, Guangzhou, Guangdong 510620, China.
Li ZH; Department of Clinical Laboratory, Guangzhou Twelfth People's Hospital, Guangzhou, Guangdong 510620, China.
Liu ZM; Stomatology Major, Medical College of Jinzhou Medical University, Jinzhou, Liaoning, China.
Wu SG; Department of Clinical Laboratory, Guangzhou Twelfth People's Hospital, Guangzhou, Guangdong 510620, China. Electronic address: 956738167@qq.com.
Hu YW; Department of Laboratory Medicine Center, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong 510515, China; Department of Clinical Laboratory, Guangzhou Women and Children's Medical Center, Guangzhou, Guangdong 510623, China. Electronic address: ywhu0618@163.com.

Immunobiology ; 226(5): 152133, 2021 09.

Article em En | MEDLINE | ID: mdl-34469785

Assuntos

Células Endoteliais da Veia Umbilical Humana; NF-kappa B; Piroptose; RNA Longo não Codificante; Receptor 4 Toll-Like; Aterosclerose/genética; Proteínas Adaptadoras de Sinalização CARD/genética; Caspase 1/genética; Células Cultivadas; Células Endoteliais da Veia Umbilical Humana/efeitos dos fármacos; Células Endoteliais da Veia Umbilical Humana/metabolismo; Humanos; Inflamassomos/genética; Inflamassomos/metabolismo; Interleucina-18/genética; Interleucina-1beta/genética; Lipopolissacarídeos/farmacologia; NF-kappa B/genética; NF-kappa B/metabolismo; Proteína 3 que Contém Domínio de Pirina da Família NLR/genética; Proteína 3 que Contém Domínio de Pirina da Família NLR/metabolismo; Piroptose/efeitos dos fármacos; RNA Mensageiro; Transdução de Sinais/efeitos dos fármacos; Receptor 4 Toll-Like/genética; Receptor 4 Toll-Like/metabolismo

Palavras-chave

Atherosclerosis; Lipopolysaccharide; Pyroptosis; lncRNA

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: NF-kappa B / Receptor 4 Toll-Like / Células Endoteliais da Veia Umbilical Humana / RNA Longo não Codificante / Piroptose Limite: Humans Idioma: En Revista: Immunobiology Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China País de publicação: Holanda

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