Intracellular activation of 4-hydroxycyclophosphamide into a DNA-alkylating agent in human leucocytes.

Yong, Minghan; Burns, Kathryn Elisa; de Zoysa, Janak; Helsby, Nuala Ann

Yong, Minghan; Burns, Kathryn Elisa; de Zoysa, Janak; Helsby, Nuala Ann.

Afiliação

Yong M; The University of Auckland Faculty of Medical and Health Sciences, Molecular Medicine and Pathology, Auckland, New Zealand.
Burns KE; The University of Auckland Faculty of Medical and Health Sciences, Molecular Medicine and Pathology, Auckland, New Zealand.
de Zoysa J; North Shore Hospital, Waitemata District Health Board, Auckland, New Zealand.
Helsby NA; Faculty of Medical and Health Sciences, The University of Auckland School of Medicine, Auckland, New Zealand.

Xenobiotica ; 51(10): 1188-1198, 2021 Oct.

Article em En | MEDLINE | ID: mdl-34470569

Assuntos

Alquilantes; Leucócitos Mononucleares; Células CACO-2; Ciclofosfamida/análogos & derivados; DNA; Humanos; Mostardas de Fosforamida

Palavras-chave

4-hydroxyclophosphamide; DNA-alkylating; activation; enzyme; phosphodiesterase

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucócitos Mononucleares / Alquilantes Limite: Humans Idioma: En Revista: Xenobiotica Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Nova Zelândia País de publicação: Reino Unido

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google