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HspB8 prevents aberrant phase transitions of FUS by chaperoning its folded RNA-binding domain.
Boczek, Edgar E; Fürsch, Julius; Niedermeier, Marie Laura; Jawerth, Louise; Jahnel, Marcus; Ruer-Gruß, Martine; Kammer, Kai-Michael; Heid, Peter; Mediani, Laura; Wang, Jie; Yan, Xiao; Pozniakovski, Andrej; Poser, Ina; Mateju, Daniel; Hubatsch, Lars; Carra, Serena; Alberti, Simon; Hyman, Anthony A; Stengel, Florian.
Afiliação
  • Boczek EE; Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.
  • Fürsch J; Dewpoint Therapeutics GmbH, Dresden, Germany.
  • Niedermeier ML; University of Konstanz, Department of Biology, Konstanz, Germany.
  • Jawerth L; Konstanz Research School Chemical Biology, University of Konstanz, Konstanz, Germany.
  • Jahnel M; University of Konstanz, Department of Biology, Konstanz, Germany.
  • Ruer-Gruß M; Konstanz Research School Chemical Biology, University of Konstanz, Konstanz, Germany.
  • Kammer KM; Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.
  • Heid P; Max Planck Institute for the Physics of Complex Systems, Dresden, Germany.
  • Mediani L; Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.
  • Wang J; Biotechnology Center, Technische Universität Dresden, Dresden, Germany.
  • Yan X; Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.
  • Pozniakovski A; University of Konstanz, Department of Biology, Konstanz, Germany.
  • Poser I; Konstanz Research School Chemical Biology, University of Konstanz, Konstanz, Germany.
  • Mateju D; University of Konstanz, Department of Biology, Konstanz, Germany.
  • Hubatsch L; Konstanz Research School Chemical Biology, University of Konstanz, Konstanz, Germany.
  • Carra S; Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy.
  • Alberti S; Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.
  • Hyman AA; Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.
  • Stengel F; Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.
Elife ; 102021 09 06.
Article em En | MEDLINE | ID: mdl-34487489

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: RNA / Chaperonas Moleculares / Proteína FUS de Ligação a RNA / Proteínas de Choque Térmico Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Elife Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Alemanha País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: RNA / Chaperonas Moleculares / Proteína FUS de Ligação a RNA / Proteínas de Choque Térmico Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Elife Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Alemanha País de publicação: Reino Unido