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Physiologically-Based Pharmacokinetic Modelling of Entrectinib Parent and Active Metabolite to Support Regulatory Decision-Making.
Djebli, Nassim; Buchheit, Vincent; Parrott, Neil; Guerini, Elena; Cleary, Yumi; Fowler, Stephen; Frey, Nicolas; Yu, Li; Mercier, François; Phipps, Alex; Meneses-Lorente, Georgina.
Afiliação
  • Djebli N; Roche Pharmaceutical Research and Early Development, Roche Innovation Center, F. Hoffmann-La Roche Ltd, Basel, Switzerland. nassim.djebli@roche.com.
  • Buchheit V; Roche Pharmaceutical Research and Early Development, Roche Innovation Center, F. Hoffmann-La Roche Ltd, Basel, Switzerland.
  • Parrott N; Roche Pharmaceutical Research and Early Development, Roche Innovation Center, F. Hoffmann-La Roche Ltd, Basel, Switzerland.
  • Guerini E; Roche Pharmaceutical Research and Early Development, Roche Innovation Center, F. Hoffmann-La Roche Ltd, Basel, Switzerland.
  • Cleary Y; Roche Pharmaceutical Research and Early Development, Roche Innovation Center, F. Hoffmann-La Roche Ltd, Basel, Switzerland.
  • Fowler S; Roche Pharmaceutical Research and Early Development, Roche Innovation Center, F. Hoffmann-La Roche Ltd, Basel, Switzerland.
  • Frey N; Roche Pharmaceutical Research and Early Development, Roche Innovation Center, F. Hoffmann-La Roche Ltd, Basel, Switzerland.
  • Yu L; Roche Pharmaceutical Research and Early Development, Roche Innovation Center, Jersey City, NJ, USA.
  • Mercier F; Roche Pharmaceutical Research and Early Development, Roche Innovation Center, F. Hoffmann-La Roche Ltd, Basel, Switzerland.
  • Phipps A; Roche Pharmaceutical Research and Early Development, Roche Innovation Center, Roche Products Ltd, Welwyn, UK.
  • Meneses-Lorente G; Roche Pharmaceutical Research and Early Development, Roche Innovation Center, Roche Products Ltd, Welwyn, UK.
Eur J Drug Metab Pharmacokinet ; 46(6): 779-791, 2021 Nov.
Article em En | MEDLINE | ID: mdl-34495458
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Benzamidas / Indazóis Tipo de estudo: Guideline / Prognostic_studies Limite: Humans Idioma: En Revista: Eur J Drug Metab Pharmacokinet Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Suíça País de publicação: França
Texto completo
Adicionar na Minha BVS
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Benzamidas / Indazóis Tipo de estudo: Guideline / Prognostic_studies Limite: Humans Idioma: En Revista: Eur J Drug Metab Pharmacokinet Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Suíça País de publicação: França