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Viper venoms drive the macrophages and hepatocytes to sequester and clear platelets: novel mechanism and therapeutic strategy for venom-induced thrombocytopenia.
Shen, Chuanbin; Liu, Ming; Mackeigan, Daniel Thomas; Chen, Zi Yan; Chen, Pingguo; Karakas, Danielle; Li, June; Norris, Peter A A; Li, Jiayao; Deng, Yanling; Long, Chengbo; Lai, Ren; Ni, Heyu.
Afiliação
  • Shen C; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, M5S 1A1, Canada.
  • Liu M; Department of Laboratory Medicine, LKSKI-Keenan Research Centre for Biomedical Science, St. Michael's Hospital, and Toronto Platelet Immunobiology Group, Toronto, ON, M5B 1W8, Canada.
  • Mackeigan DT; Department of Molecular and Cell Biology, School of Life Sciences, University of Science and Technology of China, Hefei, 230027, Anhui, China.
  • Chen ZY; Department of Laboratory Medicine, LKSKI-Keenan Research Centre for Biomedical Science, St. Michael's Hospital, and Toronto Platelet Immunobiology Group, Toronto, ON, M5B 1W8, Canada.
  • Chen P; Department of Physiology, University of Toronto, Toronto, ON, M5S 1A1, Canada.
  • Karakas D; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, M5S 1A1, Canada.
  • Li J; Department of Laboratory Medicine, LKSKI-Keenan Research Centre for Biomedical Science, St. Michael's Hospital, and Toronto Platelet Immunobiology Group, Toronto, ON, M5B 1W8, Canada.
  • Norris PAA; Canadian Blood Services Centre for Innovation, Toronto, ON, M5G 2M1, Canada.
  • Li J; Department of Laboratory Medicine, LKSKI-Keenan Research Centre for Biomedical Science, St. Michael's Hospital, and Toronto Platelet Immunobiology Group, Toronto, ON, M5B 1W8, Canada.
  • Deng Y; Canadian Blood Services Centre for Innovation, Toronto, ON, M5G 2M1, Canada.
  • Long C; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, M5S 1A1, Canada.
  • Lai R; Department of Laboratory Medicine, LKSKI-Keenan Research Centre for Biomedical Science, St. Michael's Hospital, and Toronto Platelet Immunobiology Group, Toronto, ON, M5B 1W8, Canada.
  • Ni H; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, M5S 1A1, Canada.
Arch Toxicol ; 95(11): 3589-3599, 2021 Nov.
Article em En | MEDLINE | ID: mdl-34519865
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Trombocitopenia / Venenos de Víboras / Hepatócitos / Macrófagos Limite: Animals / Female / Humans / Male Idioma: En Revista: Arch Toxicol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Canadá País de publicação: Alemanha
Texto completo
Adicionar na Minha BVS
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Trombocitopenia / Venenos de Víboras / Hepatócitos / Macrófagos Limite: Animals / Female / Humans / Male Idioma: En Revista: Arch Toxicol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Canadá País de publicação: Alemanha