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Phenyl-Glutarimides: Alternative Cereblon Binders for the Design of PROTACs.
Min, Jaeki; Mayasundari, Anand; Keramatnia, Fatemeh; Jonchere, Barbara; Yang, Seung Wook; Jarusiewicz, Jamie; Actis, Marisa; Das, Sourav; Young, Brandon; Slavish, Jake; Yang, Lei; Li, Yong; Fu, Xiang; Garrett, Shalandus H; Yun, Mi-Kyung; Li, Zhenmei; Nithianantham, Stanley; Chai, Sergio; Chen, Taosheng; Shelat, Anang; Lee, Richard E; Nishiguchi, Gisele; White, Stephen W; Roussel, Martine F; Potts, Patrick Ryan; Fischer, Marcus; Rankovic, Zoran.
Afiliação
  • Min J; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.
  • Mayasundari A; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.
  • Keramatnia F; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.
  • Jonchere B; Department of Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.
  • Yang SW; Department of Cell & Molecular Biology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.
  • Jarusiewicz J; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.
  • Actis M; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.
  • Das S; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.
  • Young B; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.
  • Slavish J; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.
  • Yang L; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.
  • Li Y; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.
  • Fu X; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.
  • Garrett SH; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.
  • Yun MK; Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.
  • Li Z; Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.
  • Nithianantham S; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.
  • Chai S; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.
  • Chen T; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.
  • Shelat A; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.
  • Lee RE; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.
  • Nishiguchi G; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.
  • White SW; Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.
  • Roussel MF; Department of Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.
  • Potts PR; Department of Cell & Molecular Biology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.
  • Fischer M; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.
  • Rankovic Z; Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.
Angew Chem Int Ed Engl ; 60(51): 26663-26670, 2021 12 13.
Article em En | MEDLINE | ID: mdl-34614283
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piperidonas / Ubiquitina-Proteína Ligases / Proteínas Adaptadoras de Transdução de Sinal Limite: Humans Idioma: En Revista: Angew Chem Int Ed Engl Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piperidonas / Ubiquitina-Proteína Ligases / Proteínas Adaptadoras de Transdução de Sinal Limite: Humans Idioma: En Revista: Angew Chem Int Ed Engl Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos