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Design, synthesis and biological evaluation of tyrosinase-targeting PROTACs.
Fu, Dingqiang; Yuan, Yi; Qin, Fengming; Xu, Yan; Cui, Xin; Li, Guangxun; Yao, Shaohua; Deng, Yun; Tang, Zhuo.
Afiliação
  • Fu D; Natural Products Research Center, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu, 610041, China; University of Chinese Academy of Sciences, Beijing, 100049, China.
  • Yuan Y; Natural Products Research Center, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu, 610041, China.
  • Qin F; Laboratory of Biotherapy, National Key Laboratory of Biotherapy, Cancer Center, West China Hospital, Sichuan University, Chengdu, 610041, China.
  • Xu Y; Natural Products Research Center, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu, 610041, China.
  • Cui X; Natural Products Research Center, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu, 610041, China.
  • Li G; Natural Products Research Center, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu, 610041, China. Electronic address: Ligx@cib.ac.cn.
  • Yao S; Laboratory of Biotherapy, National Key Laboratory of Biotherapy, Cancer Center, West China Hospital, Sichuan University, Chengdu, 610041, China.
  • Deng Y; State Key Laboratory of Southwestern Chinese Medicine Resources, The Ministry of Education Key Laboratory of Standardization of Chinese Herbal Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China. Electronic address: dengyun2000@hotmail.com.
  • Tang Z; Natural Products Research Center, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu, 610041, China. Electronic address: tangzhuo@cib.ac.cn.
Eur J Med Chem ; 226: 113850, 2021 Dec 15.
Article em En | MEDLINE | ID: mdl-34628235

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pironas / Desenho de Fármacos / Monofenol Mono-Oxigenase / Inibidores Enzimáticos Limite: Humans Idioma: En Revista: Eur J Med Chem Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China País de publicação: França

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pironas / Desenho de Fármacos / Monofenol Mono-Oxigenase / Inibidores Enzimáticos Limite: Humans Idioma: En Revista: Eur J Med Chem Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China País de publicação: França